Incidence and variables associated with arrhythmias during dobutamine-atropine stress echocardiography among patients with Chagas disease.

A new interesting article has been published in Echocardiography. 2019 Jul;36(7):1338-1345. doi: 10.1111/echo.14341. Epub 2019 Jul 2. and titled:

Incidence and variables associated with arrhythmias during dobutamine-atropine stress echocardiography among patients with Chagas disease.

Authors of this article are:

Carmo Rassi D, Tiemi Hotta V, Gomes Furtado R, Campos Vieira ML, Paula Turco F, Henrique Melato L, Godoy Nunes C, Rassi L Jr, Rassi S.

A summary of the article is shown below:

BACKGROUND: Dobutamine stress echocardiography (DSE) is an important tool in the diagnosis of coronary artery disease. However, there is hesitation in clinical practice for using it in patients with Chagas disease (CD) due to the arrhythmogenic potential of this heart condition. This study aimed to evaluate the incidence and variables associated with arrhythmias during DSE in a population of patients with CD.METHODS: A population of 205 consecutive patients with CD and suspected coronary heart disease was assessed through a retrospective database analysis. CD was confirmed in all patients by serological testing.RESULTS: The mean age of the patients selected was 64 years, and 65.4% of the patients were female. Significant arrhythmias occurred as follows: nonsustained ventricular tachycardia in 7.3% of patients; supraventricular tachycardia and sustained ventricular tachycardia in 1%; and atrial fibrillation in 0.5%. Nonsignificant arrhythmias occurred as follows: premature ventricular contractions in 48% of patients and bigeminy in 4.4%. Values for the wall-motion score index at rest greater than 1.12 and 1.18 were independently correlated with the occurrence of nonsignificant arrhythmias (odds ratio [OR] = 2.90, P < 0.001) and significant arrhythmias (OR = 4.23, P = 0.044), respectively.CONCLUSION: DSE should be considered a safe examination in patients with CD despite the known increased risk of arrhythmias in this group of patients. The occurrence of arrhythmias was low in this study. Abnormal wall-motion score index values at rest were associated with the occurrence of significant and nonsignificant arrhythmias during the test.© 2019 Wiley Periodicals, Inc.
Check out the article’s website on Pubmed for more information:

[link-preview url=https://www.ncbi.nlm.nih.gov/pubmed/31264737 forceshot=true]

This article is a good source of information and a good way to become familiar with topics such as: Chagas disease;arrhythmias;dobutamine stress echocardiography.

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