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Human Retinol-binding Protein 4 (RBP4) Free Form

Original price was: $1,595.00.Current price is: $795.00.

Catalog Number: B2016420 (50 ug)
Human Retinol-binding Protein 4 (RBP4) Free Form is a high quality protein involved in the transport of retinol (vitamin A) in the blood. RBP4 is produced by the liver and binds to retinol, helping to transport it to various tissues in the body. The “free form” of RBP4 refers to the protein being unbound to retinol, which allows it to circulate in the blood and perform other functions beyond retinol transport. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

Human Retinol-binding Protein 4 (RBP4) Free Form
Catalog number: B2016420
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 ug
Molecular Weight or Concentration: N/A
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Retinol-binding protein 4 (RBP4) from human plasma free form
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Ingenbleek Y, Bernstein LH. Plasma Transthyretin as a Biomarker of Lean Body Mass and Catabolic States Adv Nutr. 2015 Sep 15;6(5):572-80.
2: Barazzoni R, Zanetti M, Semolic A, Pirulli A, Cattin MR, Biolo G, Bosutti A, Panzetta G, Bernardi A, Guarnieri G. High plasma retinol binding protein 4 (RBP4) is associated with systemic inflammation independently of low RBP4 adipose expression and is normalized by transplantation in nonobese, nondiabetic patients with chronic kidney disease Clin Endocrinol (Oxf). 2011 Jul;75(1):56-63.
3: Karakas SE, Banaszewska B, Spaczynski RZ, Pawelczyk L, Duleba A. Free fatty acid binding protein-4 and retinol binding protein-4 in polycystic ovary syndrome: response to simvastatin and metformin therapies Gynecol Endocrinol. 2013 May;29(5):483-7.
4: Ortega-Senovilla H, de Oya M, Garcés C. Relationship of NEFA concentrations to RBP4 and to RBP4/retinol in prepubertal children with and without obesity J Clin Lipidol. 2019 Mar-Apr;13(2):301-307.
5: Cabré A, Lázaro I, Girona J, Manzanares J, Marimón F, Plana N, Heras M, Masana L. Retinol-binding protein 4 as a plasma biomarker of renal dysfunction and cardiovascular disease in type 2 diabetes J Intern Med. 2007 Oct;262(4):496-503.
6: Sobotka R, Čapoun O, Kalousová M, Hanuš T, Zima T, Koštířová M, Soukup V. Prognostic Importance of Vitamins A, E and Retinol-binding Protein 4 in Renal Cell Carcinoma Patients Anticancer Res. 2017 Jul;37(7):3801-3806.
7: Li X, Lyu Y, Shen J, Mu Y, Qiang L, Liu L, Araki K, Imbimbo BP, Yamamura KI, Jin S, Li Z. Amyloid deposition in a mouse model humanized at the transthyretin and retinol-binding protein 4 loci Lab Invest. 2018 Apr;98(4):512-524.
8: Olszanecka-Glinianowicz M, Madej P, Zdun D, Bożentowicz-Wikarek M, Sikora J, Chudek J, Skałba P. Are plasma levels of visfatin and retinol-binding protein 4 (RBP4) associated with body mass, metabolic and hormonal disturbances in women with polycystic ovary syndrome? Eur J Obstet Gynecol Reprod Biol. 2012 May;162(1):55-61.
9: Frey SK, Spranger J, Henze A, Pfeiffer AF, Schweigert FJ, Raila J. Factors that influence retinol-binding protein 4-transthyretin interaction are not altered in overweight subjects and overweight subjects with type 2 diabetes mellitus Metabolism. 2009 Oct;58(10):1386-92.
10: Chen Y, Lv P, Du M, Liang Z, Zhou M, Chen D. Increased retinol-free RBP4 contributes to insulin resistance in gestational diabetes mellitus Arch Gynecol Obstet. 2017 Jul;296(1):53-61.

Products Related to Human Retinol-binding Protein 4 (RBP4) Free Form can be found at Proteins

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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