Human LD4 1H3M Native

Product Description

Human LD4 1H3M Native
Catalog number: B2017001
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 U
Molecular Weight or Concentration: N/A
Supplied as: Suspension
Applications: a molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: DH4, LDHD, MGC57726, 1H3M isoenzyme
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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2: Sheibani N, Tang Y, Sorenson CM. Paxillin’s LD4 motif interacts with bcl-2 J Cell Physiol. 2008 Mar;214(3):655-61.
3: Antoniades I, Kyriakou M, Charalambous A, Kalalidou K, Christodoulou A, Christoforou M, Skourides PA. FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer progression and metastasis Cell Commun Signal. 2021 Jan 7;19(1):3.
4: Tao Z, Li X, Yu H, Wu J, Wen Y, Liu T. Photodynamic Therapy of LD4-Photosensitizer Attenuates the Acute Pneumonia Induced by Klebsiella pneumoniae ACS Pharmacol Transl Sci. 2024 Mar 5;7(4):1101-1113.
5: Rummel A. Two Feet on the Membrane: Uptake of Clostridial Neurotoxins Curr Top Microbiol Immunol. 2017;406:1-37.
6: Turner CE, Brown MC, Perrotta JA, Riedy MC, Nikolopoulos SN, McDonald AR, Bagrodia S, Thomas S, Leventhal PS. Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling J Cell Biol. 1999 May 17;145(4):851-63.
7: Nocula-Lugowska M, Lugowski M, Salgia R, Kossiakoff AA. Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin J Mol Biol. 2015 Jul 31;427(15):2532-2547.
8: Mahrhold S, Bergström T, Stern D, Dorner BG, Åstot C, Rummel A. Only the complex N559-glycan in the synaptic vesicle glycoprotein 2C mediates high affinity binding to botulinum neurotoxin serotype A1 Biochem J. 2016 Sep 1;473(17):2645-54.
9: Lulo J, Yuzawa S, Schlessinger J. Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2 Biochem Biophys Res Commun. 2009 Jun 5;383(3):347-52.
10: West KA, Zhang H, Brown MC, Nikolopoulos SN, Riedy MC, Horwitz AF, Turner CE. The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL) J Cell Biol. 2001 Jul 9;154(1):161-76.

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