Human Complement C4 Deficient Heparin Plasma

Product Description

Human Complement C4 Deficient Heparin Plasma
Catalog number: B2015074
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mL
Molecular Weight or Concentration: N/A
Supplied as: Plasma
Applications: molecular tool for various biochemical applications
Storage: -20° C
Keywords: Complement Component 4, Complement Component IV, C4, CIV, Acidic C4, Acidic Complement C4, Basic C4, C3 and PZP-like alpha-2-Macroglobulin Domain-containing Protein 2, C4 Anaphylatoxin
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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2: Majluf-Cruz A, Nieto-Martínez S. Long-term follow up analysis of nadroparin for hereditary angioedema. A preliminary report Int Immunopharmacol. 2011 Aug;11(8):1127-32.
3: Thorisdottir H, Evans JA, Schwartz HJ, Comp P, Haluschak J, Ratnoff OD. Some clotting factors in plasma during danazol therapy: free and total protein S, but not C4b-binding protein, are elevated by danazol therapy J Lab Clin Med. 1992 Jun;119(6):698-701.
4: Hopen G, Glette J, Matre R. Mechanisms of decreased leucocyte adhesiveness and migration in plasma from patients with IgG myelomatosis Scand J Haematol. 1984 Jan;32(1):88-94.
5: Lundtoft C, Sjöwall C, Rantapää-Dahlqvist S, Bengtsson AA, Jönsen A, Pucholt P, Wu YL, Lundström E, Eloranta ML, Gunnarsson I, Baecklund E, Jonsson R, Hammenfors D, Forsblad-d’Elia H, Eriksson P, Mandl T, Bucher S, Norheim KB, Auglaend Johnsen SJ, Omdal R, Kvarnström M, Wahren-Herlenius M, Truedsson L, Nilsson B, Kozyrev SV, Bianchi M, Lindblad-Toh K; DISSECT consortium, the ImmunoArray consortium; Yu CY, Nordmark G, Sandling JK, Svenungsson E, Leonard D, Rönnblom L. Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren’s Syndrome Arthritis Rheumatol. 2022 Nov;74(11):1842-1850.
6: Kaplan AP, Joseph K. Complement, Kinins, and Hereditary Angioedema: Mechanisms of Plasma Instability when C1 Inhibitor is Absent Clin Rev Allergy Immunol. 2016 Oct;51(2):207-15.
7: Davis AE 3rd. The pathophysiology of hereditary angioedema Clin Immunol. 2005 Jan;114(1):3-9.
8: Stites E, Renner B, Laskowski J, Le Quintrec M, You Z, Freed B, Cooper J, Jalal D, Thurman JM. Complement fragments are biomarkers of antibody-mediated endothelial injury Mol Immunol. 2020 Feb;118:142-152.
9: Aabom A, Bygum A, Koch C. Complement factor C4 activation in patients with hereditary angioedema Clin Biochem. 2017 Oct;50(15):816-821.
10: Dalmasso AP. Complement in the pathophysiology and diagnosis of human diseases Crit Rev Clin Lab Sci. 1986;24(2):123-83.

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