Human Complement C3 Deficient Sodium Citrate Plasma

Product Description

Human Complement C3 Deficient Sodium Citrate Plasma
Catalog number: B2015134
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mL
Molecular Weight or Concentration: N/A
Supplied as: Plasma
Applications: molecular tool for various biochemical applications
Storage: -20° C
Keywords: Complement Component 3, Complement Component III, Complement Factor 3, Complement CIII, CIII, C3
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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2: Yuan Y, Yan D, Han G, Gu G, Ren J. Complement C3 depletion links to the expansion of regulatory T cells and compromises T-cell immunity in human abdominal sepsis: a prospective pilot study J Crit Care. 2013 Dec;28(6):1032-8.
3: Alexander JJ, Hack BK, Jacob A, Chang A, Haas M, Finberg RW, Quigg RJ. Abnormal immune complex processing and spontaneous glomerulonephritis in complement factor H-deficient mice with human complement receptor 1 on erythrocytes J Immunol. 2010 Sep 15;185(6):3759-67.
4: Naik A, Sharma S, Quigg RJ. Complement regulation in renal disease models Semin Nephrol. 2013 Nov;33(6):575-85.
5: Whaley K, Schwaeble W. Complement and complement deficiencies Semin Liver Dis. 1997;17(4):297-310.
6: Smith-Jackson K, Yang Y, Denton H, Pappworth IY, Cooke K, Barlow PN, Atkinson JP, Liszewski MK, Pickering MC, Kavanagh D, Cook HT, Marchbank KJ. Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice J Clin Invest. 2019 Mar 1;129(3):1061-1075.
7: de Boer E, Sokolova M, Quach HQ, McAdam KE, Götz MP, Chaban V, Vaage J, Fageräng B, Woodruff TM, Garred P, Nilsson PH, Mollnes TE, Pischke SE. Synthetic Oligodeoxynucleotide CpG Motifs Activate Human Complement through Their Backbone Structure and Induce Complement-Dependent Cytokine Release J Immunol. 2022 Nov 1;209(9):1760-1767.
8: Reis ES, Berger N, Wang X, Koutsogiannaki S, Doot RK, Gumas JT, Foukas PG, Resuello RRG, Tuplano JV, Kukis D, Tarantal AF, Young AJ, Kajikawa T, Soulika AM, Mastellos DC, Yancopoulou D, Biglarnia AR, Huber-Lang M, Hajishengallis G, Nilsson B, Lambris JD. Safety profile after prolonged C3 inhibition Clin Immunol. 2018 Dec;197:96-106.
9: Bogomolova AM, Shavva VS, Nikitin AA, Nekrasova EV, Dizhe EB, Larionova EE, Kudriavtsev IV, Orlov SV. Hypoxia as a Factor Involved in the Regulation of the apoA-1, ABCA1, and Complement C3 Gene Expression in Human Macrophages Biochemistry (Mosc). 2019 May;84(5):529-539.
10: Brown DL, Lachmann PJ, Dacie JV. The in vivo behaviour of complement-coated red cells: studies in C6-deficient, C3-depleted and normal rabbits Clin Exp Immunol. 1970 Sep;7(3):401-21.

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