Human Alpha-1-Antitrypsin Deficient Sodium Citrate Plasma

Product Description

Human Alpha-1-Antitrypsin Deficient Sodium Citrate Plasma
Catalog number: B2015072
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mL
Molecular Weight or Concentration: N/A
Supplied as: Plasma, Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20° C
Keywords: alpha-1-Antitripsin, A1AT, Alpha-1 Protease Inhibitor, Alpha-1-Antiproteinase, Serpin A1, SPAAT, SERPINA1, AAT
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Lomas DA, Elliott PR, Carrell RW. Commercial plasma alpha1-antitrypsin (Prolastin) contains a conformationally inactive, latent component Eur Respir J. 1997 Mar;10(3):672-5.
2: Sandhaus RA, Turino G, Brantly ML, Campos M, Cross CE, Goodman K, Hogarth DK, Knight SL, Stocks JM, Stoller JK, Strange C, Teckman J. The Diagnosis and Management of Alpha-1 Antitrypsin Deficiency in the Adult Chronic Obstr Pulm Dis. 2016 Jun 6;3(3):668-682.
3: Greene CM, Marciniak SJ, Teckman J, Ferrarotti I, Brantly ML, Lomas DA, Stoller JK, McElvaney NG. α1-Antitrypsin deficiency Nat Rev Dis Primers. 2016 Jul 28;2:16051.
4: Mornex JF. [Alpha 1-antitrypsin deficiency] Rev Mal Respir. 2022 Oct;39(8):698-707.
5: Fraughen DD, Ghosh AJ, Hobbs BD, Funk GC, Meischl T, Clarenbach CF, Sievi NA, Schmid-Scherzer K, McElvaney OJ, Murphy MP, Roche AD, Clarke L, Strand M, Vafai-Tabrizi F, Kelly G, Gunaratnam C, Carroll TP, McElvaney NG. Augmentation Therapy for Severe Alpha-1 Antitrypsin Deficiency Improves Survival and Is Decoupled from Spirometric Decline-A Multinational Registry Analysis Am J Respir Crit Care Med. 2023 Nov 1;208(9):964-974.
6: Cazzola M, Stolz D, Rogliani P, Matera MG. α(1)-Antitrypsin deficiency and chronic respiratory disorders Eur Respir Rev. 2020 Feb 12;29(155):190073.
7: Wewers MD, Crystal RG. Alpha-1 antitrypsin augmentation therapy COPD. 2013 Mar;10 Suppl 1:64-7.
8: Berger M, Liu M, Uknis ME, Koulmanda M. Alpha-1-antitrypsin in cell and organ transplantation Am J Transplant. 2018 Jul;18(7):1589-1595.
9: Sark AD, Fromme M, Olejnicka B, Welte T, Strnad P, Janciauskiene S, Stolk J. The Relationship between Plasma Alpha-1-Antitrypsin Polymers and Lung or Liver Function in ZZ Alpha-1-Antitrypsin-Deficient Patients Biomolecules. 2022 Feb 28;12(3):380.
10: Serban KA, Pratte KA, Strange C, Sandhaus RA, Turner AM, Beiko T, Spittle DA, Maier L, Hamzeh N, Silverman EK, Hobbs BD, Hersh CP, DeMeo DL, Cho MH, Bowler RP. Unique and shared systemic biomarkers for emphysema in Alpha-1 Antitrypsin deficiency and chronic obstructive pulmonary disease EBioMedicine. 2022 Oct;84:104262.

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