Human Alpha-1-Antitrypsin Deficient Heparin Plasma

Product Description

Human Alpha-1-Antitrypsin Deficient Heparin Plasma
Catalog number: B2014886
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mL
Molecular Weight or Concentration: N/A
Supplied as: Lyophilized Plasma
Applications: molecular tool for various biochemical applications
Storage: -20° C
Keywords: alpha-1-Antitripsin, A1AT, Alpha-1 Protease Inhibitor, Alpha-1-Antiproteinase, Serpin A1, SPAAT, SERPINA1, AAT
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Beresford CH. Antithrombin III deficiency Blood Rev. 1988 Dec;2(4):239-50.
2: Heeb MJ, Griffin JH. Physiologic inhibition of human activated protein C by alpha 1-antitrypsin J Biol Chem. 1988 Aug 25;263(24):11613-6.
3: van der Meer FJ, van Tilburg NH, van Wijngaarden A, van der Linden IK, Briët E, Bertina RM. A second plasma inhibitor of activated protein C: alpha 1-antitrypsin Thromb Haemost. 1989 Sep 29;62(2):756-62.
4: Belorgey D, Hägglöf P, Karlsson-Li S, Lomas DA. Protein misfolding and the serpinopathies Prion. 2007 Jan-Mar;1(1):15-20.
5: Lane DA, Olds RR, Thein SL. Antithrombin and its deficiency states Blood Coagul Fibrinolysis. 1992 Jun;3(3):315-41.
6: Gooptu B, Lomas DA. Conformational pathology of the serpins: themes, variations, and therapeutic strategies Annu Rev Biochem. 2009;78:147-76.
7: Borsodi AD, Bradshaw RA. Isolation of antithrombin III from normal and alpha1-antitrypsin-deficient human plasma Thromb Haemost. 1977 Aug 31;38(2):475-85.
8: Kounnas MZ, Church FC, Argraves WS, Strickland DK. Cellular internalization and degradation of antithrombin III-thrombin, heparin cofactor II-thrombin, and alpha 1-antitrypsin-trypsin complexes is mediated by the low density lipoprotein receptor-related protein J Biol Chem. 1996 Mar 15;271(11):6523-9.
9: Bauer KA, Goodman TL, Kass BL, Rosenberg RD. Elevated factor Xa activity in the blood of asymptomatic patients with congenital antithrombin deficiency J Clin Invest. 1985 Aug;76(2):826-36.
10: Gram J. The haemostatic balance in groups of thrombosis-prone patients. With particular reference to fibrinolysis in patients with myocardial infarction Dan Med Bull. 1990 Jun;37(3):210-34.

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