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CTBP1 Protein

Original price was: $1,995.00.Current price is: $995.00.

Catalog Number: B2016654 (25 µg)
CTBP1 Protein is a high quality multifunctional protein that plays a role in various cellular processes, including gene regulation, cell proliferation, and apoptosis. It is involved in the regulation of metabolism, cell signaling, and cellular stress response. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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Product Description

CTBP1 Protein
Catalog number: B2016654
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 µg
Molecular Weight or Concentration: 51.1 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: CtBP1, C-terminal binding protein 1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Ren L, Qing X, Wei J, Mo H, Liu Y, Zhi Y, Lu W, Zheng M, Zhang W, Chen Y, Zhang Y, Pan T, Zhong Q, Li R, Zhang X, Ruan X, Yu R, Li J. The DDUP protein encoded by the DNA damage-induced CTBP1-DT lncRNA confers cisplatin resistance in ovarian cancer Cell Death Dis. 2023 Aug 26;14(8):568.
2: Yu R, Hu Y, Zhang S, Li X, Tang M, Yang M, Wu X, Li Z, Liao X, Xu Y, Li M, Chen S, Qian W, Gong LY, Song L, Li J. LncRNA CTBP1-DT-encoded microprotein DDUP sustains DNA damage response signalling to trigger dual DNA repair mechanisms Nucleic Acids Res. 2022 Aug 12;50(14):8060-8079.
3: Ikeda M, Arai K, Masai H. CTBP1/RBP1, a Saccharomyces cerevisiae protein which binds to T-rich single-stranded DNA containing the 11-bp core sequence of autonomously replicating sequence, is a poly(deoxypyrimidine)-binding protein Eur J Biochem. 1996 May 15;238(1):38-47.
4: Erlandsen H, Jecrois AM, Nichols JC, Cole JL, Royer WE Jr. NADH/NAD(+) binding and linked tetrameric assembly of the oncogenic transcription factors CtBP1 and CtBP2 FEBS Lett. 2022 Feb;596(4):479-490.
5: He Y, He Z, Lin J, Chen C, Chen Y, Liu S. CtBP1/2 differentially regulate genomic stability and DNA repair pathway in high-grade serous ovarian cancer cell Oncogenesis. 2021 Jul 13;10(7):49.
6: Wang M, Zhao H. LncRNA CTBP1-AS2 Promotes Cell Proliferation in Hepatocellular Carcinoma by Regulating the miR-623/Cyclin D1 Axis Cancer Biother Radiopharm. 2020 Dec;35(10):765-770.
7: Miczi M, Golda M, Kunkli B, Nagy T, Tőzsér J, Mótyán JA. Identification of Host Cellular Protein Substrates of SARS-COV-2 Main Protease Int J Mol Sci. 2020 Dec 15;21(24):9523.
8: Furusawa T, Moribe H, Kondoh H, Higashi Y. Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1 Mol Cell Biol. 1999 Dec;19(12):8581-90.
9: Molloy DP, Barral PM, Gallimore PH, Grand RJ. The effect of CtBP1 binding on the structure of the C-terminal region of adenovirus 12 early region 1A Virology. 2007 Jul 5;363(2):342-56.
10: Jiang C, Trudeau SJ, Cheong TC, Guo R, Teng M, Wang LW, Wang Z, Pighi C, Gautier-Courteille C, Ma Y, Jiang S, Wang C, Zhao B, Paillard L, Doench JG, Chiarle R, Gewurz BE. CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation Cell Rep. 2019 Jul 30;28(5):1307-1322.e8.

Products Related to CTBP1 Protein can be found at Proteins

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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