Acacetin (Highly Pure)


Catalog Number: B2013158 (5 mg)
Acacetin (Highly Pure) is a high quality chemical compound with anti-proliferative and apoptosis inducing properties. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Acacetin (Highly Pure)
Catalog number: B2013158
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 284.3 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: RT
Keywords: 2-(4-Methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one, 4′-O-Methylapigenin, 5,7-Dihydroxy-4′-methoxyflavone
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Singh S, Gupta P, Meena A, Luqman S. Acacetin, a flavone with diverse therapeutic potential in cancer, inflammation, infections and other metabolic disorders Food Chem Toxicol. 2020 Nov;145:111708.
2: Cui YK, Hong YX, Wu WY, Han WM, Wu Y, Wu C, Li GR, Wang Y. Acacetin ameliorates cardiac hypertrophy by activating Sirt1/AMPK/PGC-1α pathway Eur J Pharmacol. 2022 Apr 5;920:174858.
3: Wu C, Yan J, Li W. Acacetin as a Potential Protective Compound against Cardiovascular Diseases Evid Based Complement Alternat Med. 2022 Mar 2;2022:6265198.
4: Wu C, Chen RL, Wang Y, Wu WY, Li G. Acacetin alleviates myocardial ischaemia/reperfusion injury by inhibiting oxidative stress and apoptosis via the Nrf-2/HO-1 pathway Pharm Biol. 2022 Dec;60(1):553-561.
5: Song F, Mao YJ, Hu Y, Zhao SS, Wang R, Wu WY, Li GR, Wang Y, Li G. Acacetin attenuates diabetes-induced cardiomyopathy by inhibiting oxidative stress and energy metabolism via PPAR-α/AMPK pathway Eur J Pharmacol. 2022 May 5;922:174916.
6: Jin M, Nie J, Zhu J, Li J, Fang T, Xu J, Jiang X, Chen Z, Li J, Wu F. Acacetin inhibits RANKL-induced osteoclastogenesis and LPS-induced bone loss by modulating NFATc1 transcription Biochem Biophys Res Commun. 2021 Oct 30;583:146-153.
7: Mu J, Chen H, Ye M, Zhang X, Ma H. Acacetin resists UVA photoaging by mediating the SIRT3/ROS/MAPKs pathway J Cell Mol Med. 2022 Aug;26(16):4624-4628.
8: Hong YX, Wu WY, Song F, Wu C, Li GR, Wang Y. Cardiac senescence is alleviated by the natural flavone acacetin_ via enhancing mitophagy Aging (Albany NY). 2021 Jun 27;13(12):16381-16403.
9: Liou CJ, Wu SJ, Shen SC, Chen LC, Chen YL, Huang WC. Acacetin Protects against Non-Alcoholic Fatty Liver Disease by Regulating Lipid Accumulation and Inflammation in Mice Int J Mol Sci. 2022 Apr 23;23(9):4687.
10: Zhang G, Li Z, Dong J, Zhou W, Zhang Z, Que Z, Zhu X, Xu Y, Cao N, Zhao A. Acacetin inhibits invasion, migration and TGF-β1-induced EMT of gastric cancer cells through the PI3K/Akt/Snail pathway BMC Complement Med Ther. 2022 Jan 9;22(1):10.

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