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A new interesting article has been published in J Clin Neurosci. 2019 Jul;65:28-33. doi: 10.1016/j.jocn.2019.04.018. Epub 2019 May 6. and titled:

Slowed articulation rate is associated with information processing speed decline in multiple sclerosis: A pilot study.

Authors of this article are:

Friedova L, Rusz J, Motyl J, Srpova B, Vodehnalova K, Andelova M, Novotna K, Novotny M, Ruzickova H, Tykalova T, Kubala Havrdova E, Horakova D, Uher T.

A summary of the article is shown below:

BACKGROUND: Impairment of cognition and speech are common in multiple sclerosis (MS) patients, but their relationship is not well understood.OBJECTIVE: To describe the relationship between articulation rate characteristics and processing speed and to investigate the potential role of objective speech analysis for the detection of cognitive decline in MS.METHODS: A total of 122 patients with clinically definite MS were included in this cross-sectional pilot study. Patients underwent three speaking tasks (oral diadochokinesis, reading text and monologue) and assessment of processing speed (Symbol Digit Modalities Test [SDMT], Paced Auditory Serial Addition Test-3 s [PASAT-3]). Association between articulation rate and cognition was analyzed using linear regression analysis. We estimated the area under the receiver operating characteristics curves (AUC) to evaluate the predictive accuracy of articulation rate measures for the detection of abnormal processing speed.RESULTS: We observed an association between articulation rate and cognitive measures (rho = 0.45-0.58; p < 0.001). Faster reading speed by one word per second was associated with an 18.7 point (95% confidence interval [CI] 14.9-22.5) increase of the SDMT score and 14.7 (95% CI 8.9-20.4) point increase of PASAT-3 score (both p < 0.001). AUC values of articulation rate characteristics for the identification of processing speed impairment ranged between 0.67 and 0.79. Using a cutoff of 3.10 in reading speed, we were able to identify impairment in both the SDMT and PASAT-3 with 91% sensitivity and 54% specificity.CONCLUSION: Slowed articulation rate is strongly associated with processing speed decline. Objective quantitative speech analysis identified patients with abnormal cognitive performance.Copyright © 2019 Elsevier Ltd. All rights reserved.
Check out the article’s website on Pubmed for more information:

[link-preview url=https://www.ncbi.nlm.nih.gov/pubmed/31072740 forceshot=true]

This article is a good source of information and a good way to become familiar with topics such as: Adult;Cognition Disorders;Cross-Sectional Studies;Dysarthria;Female;Humans;Male;Middle Aged;Multiple Sclerosis;Pilot Projects;ROC Curve;Regression Analysis.

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