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A new interesting article has been published in Acta Paediatr. 2019 Aug;108(8):1535-1540. doi: 10.1111/apa.14721. Epub 2019 Feb 1. and titled:

No association between Helicobacter pylori infection and gastrointestinal complaints in a large cohort of symptomatic children.

Authors of this article are:

Chobot A, Porębska J, Krzywicka A, Żabka A, Bąk-Drabik K, Pieniążek W, Dubik A, Adamczyk P, Kwiecień J.

A summary of the article is shown below:

AIM: This Polish study estimated the prevalence of the Helicobacter pylori infection in symptomatic children aged 3-18 and investigated its association with gastrointestinal complaints.METHODS: We prospectively enrolled 1984 children (54% female) with a mean age of 9.5 ± 4.1 years, from Silesia, Poland, for the Good Diagnosis Treatment Life screening programme from 2009 to 2016. They underwent a 13 C-isotope-labelled urea breath test (UBT) to assess their Helicobacter pylori status, making this the biggest Polish study to use this approach. Further analysis included parental-reported gastrointestinal symptoms and standard deviation scores (SDS) of anthropometric measurements.RESULTS: The Helicobacter pylori infection was identified in 220 (11%) children (48% female) and was independent of age and sex. The frequency of symptoms did not differ between Helicobacter positive and negative children (all p > 0.05). Children with a positive UBT result had a lower body mass SDS (-0.41 ± 0.98 versus -0.26 ± 1.01, p = 0.04) and height SDS (-0.45 ± 1.34 versus -0.23 ± 1.27, p = 0.02), but similar body mass index SDS.CONCLUSION: We found a low prevalence of Helicobacter pylori in symptomatic children, and positive UBT results were not associated with symptoms that suggested Helicobacter pylori infections. Our findings support the 2017 European and North American guidelines for Helicobacter infections in children.©2019 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Check out the article’s website on Pubmed for more information:

[link-preview url=https://www.ncbi.nlm.nih.gov/pubmed/30656740 forceshot=true]

This article is a good source of information and a good way to become familiar with topics such as: Helicobacter pylori ;Abdominal pain;Gastrointestinal symptoms;Screening programme;Urea breath test.

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