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Thrombin from Bovine Plasma (High Activity)

$495.00

Catalog Number: B2010412 (100 Units)
Thrombin from Bovine Plasma (High Activity) is a high quality research product used as very high specific activity Thrombin from bovine plasma. Thrombin is a serin protease that converts soluble fibrinogen into insoluble fibrin during the clotting process. Custom bulk orders of this product are available upon request.
Live Enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2010412 Categories: , ,

Description

Thrombin from Bovine Plasma (High Activity)
Catalog number: B2010412
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 Units
Molecular Weight or Concentration: ≥2,000 NIH units/mg protein
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: very high specific activity Thrombin from bovine plasma. Thrombin is a serin protease that converts soluble fibrinogen into insoluble fibrin during the clotting process.
Storage: -20C
Keywords: Factor Iia, Bovine Thrombin, fibrinogenase, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin
Grade: Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Tripodi A. Thrombin Generation Assay and Its Application in the Clinical
Laboratory. Clin Chem. 2016 May;62(5):699-707.

2: Bhagwat SR, Hajela K, Bhutada S, Choudhary K, Saxena M, Sharma S, Kumar A.
Identification of unexplored substrates of the serine protease, thrombin, using
N-terminomics strategy. Int J Biol Macromol. 2020 Feb 1;144:449-459.

3: Hu Q, Bao Y, Gan S, Zhang Y, Han D, Niu L. Amplified Electrochemical
Biosensing of Thrombin Activity by RAFT Polymerization. Anal Chem. 2020 Feb
18;92(4):3470-3476.

4: Billur R, Sabo TM, Maurer MC. Thrombin Exosite Maturation and Ligand Binding
at ABE II Help Stabilize PAR-Binding Competent Conformation at ABE I.
Biochemistry. 2019 Feb 26;58(8):1048-1060.

5: Wolberg AS, Campbell RA. Thrombin generation, fibrin clot formation and
hemostasis. Transfus Apher Sci. 2008 Feb;38(1):15-23.

6: Rigano J, Ng C, Nandurkar H, Ho P. Thrombin generation estimates the
anticoagulation effect of direct oral anticoagulants with significant
interindividual variability observed. Blood Coagul Fibrinolysis. 2018
Mar;29(2):148-154.
7: Xiao J , Salsbury FR . Na+-binding modes involved in thrombin’s
allosteric response as revealed by molecular dynamics simulations, correlation
networks and Markov modeling. Phys Chem Chem Phys. 2019 Feb 20;21(8):4320-4330.

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