Recombinant Rat MOG (1-125)

Description

Recombinant Rat MOG (1-125)
Catalog number: B2011482
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 1 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -80 °C
Keywords: Myelin Oligodendrocyte Glycoprotein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Olsson T, Dahlman I, Wallström E, Weissert R, Piehl F. Genetics of rat neuroinflammation J Neuroimmunol. 2000 Jul 24;107(2):191-200.
2: Bernard CC, Johns TG, Slavin A, Ichikawa M, Ewing C, Liu J, Bettadapura J. Myelin oligodendrocyte glycoprotein: a novel candidate autoantigen in multiple sclerosis J Mol Med (Berl). 1997 Feb;75(2):77-88.
3: Marta CB, Oliver AR, Sweet RA, Pfeiffer SE, Ruddle NH. Pathogenic myelin oligodendrocyte glycoprotein antibodies recognize glycosylated epitopes and perturb oligodendrocyte physiology Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):13992-7.
4: de Graaf KL, Albert M, Weissert R. Autoantigen conformation influences both B- and T-cell responses and encephalitogenicity J Biol Chem. 2012 May 18;287(21):17206-17213.
5: Adelmann M, Wood J, Benzel I, Fiori P, Lassmann H, Matthieu JM, Gardinier MV, Dornmair K, Linington C. The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat J Neuroimmunol. 1995 Dec;63(1):17-27.
6: Magni G, Pedretti S, Audano M, Caruso D, Mitro N, Ceruti S. Glial cell activation and altered metabolic profile in the spinal-trigeminal axis in a rat model of multiple sclerosis associated with the development of trigeminal sensitization Brain Behav Immun. 2020 Oct;89:268-280.
7: Galicia G, Lee DSW, Ramaglia V, Ward LA, Yam JY, Leung LYT, Li R, Handy M, Zhang J, Drohomyrecky PC, Lancaster E, Bar-Or A, Martin A, Gommerman JL. Isotype-Switched Autoantibodies Are Necessary To Facilitate Central Nervous System Autoimmune Disease in Aicda(-/-) and Ung(-/-) Mice J Immunol. 2018 Aug 15;201(4):1119-1130.
8: Gori F, Mulinacci B, Massai L, Avolio C, Caragnano M, Peroni E, Lori S, Chelli M, Papini AM, Rovero P, Lolli F. IgG and IgM antibodies to the refolded MOG(1-125) extracellular domain in humans J Neuroimmunol. 2011 Apr;233(1-2):216-20.
9: Dahm L, Ott C, Steiner J, Stepniak B, Teegen B, Saschenbrecker S, Hammer C, Borowski K, Begemann M, Lemke S, Rentzsch K, Probst C, Martens H, Wienands J, Spalletta G, Weissenborn K, Stöcker W, Ehrenreich H. Seroprevalence of autoantibodies against brain antigens in health and disease Ann Neurol. 2014 Jul;76(1):82-94.
10: El-Deeb OS, Ghanem HB, El-Esawy RO, Sadek MT. The modulatory effects of luteolin on cyclic AMP/Ciliary neurotrophic factor signaling pathway in experimentally induced autoimmune encephalomyelitis IUBMB Life. 2019 Sep;71(9):1401-1408.

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