Human Recombinant HVEM/CD270 Extracellular Domain

Product Description

Human Recombinant HVEM/CD270 Extracellular Domain
Catalog number: B2016983
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 19 kDa
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: ATAR, Herpes Virus Entry Mediator, HVEA, LIGHTR, TNFRSF14, TR2, Tumor Necrosis Factor Receptor Superfamily Member 14,
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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2: Abudukeyoumu A, Lai ZZ, Lu JJ, Zhang X, Hou DY, Dong J, Wu JN, Li MQ, Xie F. A LIGHT-HVEM/LTβR axis contributes to the fibrosis of intrauterine adhesion J Reprod Immunol. 2022 Sep;153:103693.
3: Bitra A, Nemčovičová I, Picarda G, Doukov T, Wang J, Benedict CA, Zajonc DM. Structure of human cytomegalovirus UL144, an HVEM orthologue, bound to the B and T cell lymphocyte attenuator J Biol Chem. 2019 Jul 5;294(27):10519-10529.
4: del Rio ML, Schneider P, Fernandez-Renedo C, Perez-Simon JA, Rodriguez-Barbosa JI. LIGHT/HVEM/LTβR interaction as a target for the modulation of the allogeneic immune response in transplantation Am J Transplant. 2013 Mar;13(3):541-51.
5: Olive D. [Lymphocyte coreceptors] Med Sci (Paris). 2006 Dec;22(12):1069-74.
6: Nagy A, Chakrabarti L, Kurasawa J, Mulagapati SHR, Devine P, Therres J, Chen Z, Schmelzer AE. Engineered CHO cells as a novel AAV production platform for gene therapy delivery Sci Rep. 2023 Nov 6;13(1):19210.
7: Hehlgans T, Männel DN. Recombinant, soluble LIGHT (HVEM ligand) induces increased IL-8 secretion and growth arrest in A375 melanoma cells J Interferon Cytokine Res. 2001 May;21(5):333-8.
8: Maltais JS, Lord-Dufour S, Morasse A, Stuible M, Loignon M, Durocher Y. Repressing expression of difficult-to-express recombinant proteins during the selection process increases productivity of CHO stable pools Biotechnol Bioeng. 2023 Oct;120(10):2840-2852.
9: Heo SK, Choi Y, Jeong YK, Ju LJ, Yu HM, Kim DK, Seo HJ, Lee YJ, Cheon J, Koh S, Min YJ, Noh EK, Jo JC. LIGHT (TNFSF14) enhances osteogenesis of human bone marrow-derived mesenchymal stem cells PLoS One. 2021 Feb 19;16(2):e0247368.
10: Burn Aschner C, Loh LN, Galen B, Delwel I, Jangra RK, Garforth SJ, Chandran K, Almo S, Jacobs WR Jr, Ware CF, Herold BC. HVEM signaling promotes protective antibody-dependent cellular cytotoxicity (ADCC) vaccine responses to herpes simplex viruses Sci Immunol. 2020 Aug 14;5(50):eaax2454.

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