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Human Recombinant DPP-4/CD26 Extracellular Domain

Original price was: $1,795.00.Current price is: $895.00.

Catalog Number: B2016986 (25 µg)
Human Recombinant DPP-4/CD26 Extracellular Domain is a high quality enzyme that plays a role in glucose metabolism and is a target for the treatment of type 2 diabetes. CD26 is a cell surface glycoprotein that is involved in various biological processes, including immune regulation. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2016986 Categories: , Tag:

Product Description

Human Recombinant DPP-4/CD26 Extracellular Domain
Catalog number: B2016986
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 µg
Molecular Weight or Concentration: 112 kDa
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: ADABP ADCP2 Adenosine Deaminase Complexing Protein 2, Dipeptidyl Peptidase 4, DPP-IV, T-cell Activation Antigen CD26, TP103
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Fadini GP, Albiero M, Vigili de Kreutzenberg S, Boscaro E, Cappellari R, Marescotti M, Poncina N, Agostini C, Avogaro A. Diabetes impairs stem cell and proangiogenic cell mobilization in humans Diabetes Care. 2013 Apr;36(4):943-9.
2: Letko M, Marzi A, Munster V. Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses Nat Microbiol. 2020 Apr;5(4):562-569.
3: Kang K, Wu Y, Han C, Wang L, Wang Z, Zhao A. Homologous recombination deficiency in triple-negative breast cancer: Multi-scale transcriptomics reveals distinct tumor microenvironments and limitations in predicting immunotherapy response Comput Biol Med. 2023 May;158:106836.
4: Hatano R, Yamada T, Matsuoka S, Iwata S, Yamazaki H, Komiya E, Okamoto T, Dang NH, Ohnuma K, Morimoto C. Establishment of monoclonal anti-human CD26 antibodies suitable for immunostaining of formalin-fixed tissue Diagn Pathol. 2014 Feb 6;9:30.
5: Valenzuela A, Blanco J, Callebaut C, Jacotot E, Lluis C, Hovanessian AG, Franco R. HIV-1 envelope gp120 and viral particles block adenosine deaminase binding to human CD26 Adv Exp Med Biol. 1997;421:185-92.
6: Richard E, Arredondo-Vega FX, Santisteban I, Kelly SJ, Patel DD, Hershfield MS. The binding site of human adenosine deaminase for CD26/Dipeptidyl peptidase IV: the Arg142Gln mutation impairs binding to cd26 but does not cause immune deficiency J Exp Med. 2000 Nov 6;192(9):1223-36.
7: Herrera C, Morimoto C, Blanco J, Mallol J, Arenzana F, Lluis C, Franco R. Comodulation of CXCR4 and CD26 in human lymphocytes J Biol Chem. 2001 Jun 1;276(22):19532-9.
8: Ohnuma K, Inoue H, Uchiyama M, Yamochi T, Hosono O, Dang NH, Morimoto C. T-cell activation via CD26 and caveolin-1 in rheumatoid synovium Mod Rheumatol. 2006;16(1):3-13.
9: Ohnuma K, Hatano R, Itoh T, Iwao N, Dang NH, Morimoto C. Role of IL-26+CD26+CD4 T Cells in Pulmonary Chronic Graft-Versus-Host Disease and Treatment with Caveolin-1-Ig Fc Conjugate Crit Rev Immunol. 2016;36(3):239-267.
10: Tse LV, Hou YJ, McFadden E, Lee RE, Scobey TD, Leist SR, Martinez DR, Meganck RM, Schäfer A, Yount BL, Mascenik T, Powers JM, Randell SH, Zhang Y, Wang L, Mascola J, McLellan JS, Baric RS. A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus Sci Transl Med. 2023 Sep 27;15(715):eadg5567.

Products Related to Human Recombinant DPP-4/CD26 Extracellular Domain can be found at Proteins

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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