Human Recombinant B7-H3/CD276 Extracellular Domain

Product Description

Human Recombinant B7-H3/CD276 Extracellular Domain
Catalog number: B2016942
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 73.4 kDa
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: 4Ig-B7-H3, B7 Homolog 3, B7RP-2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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3: Luan Y, Ju J, Luo L, Zhang Z, Wang J, Zhu DM, Cheng L, Zhang SY, Chen L, Wang FS, Wang S. Potential role of soluble B7-H3 in liver immunopathogenesis during chronic HBV infection J Viral Hepat. 2012 Jan;19(1):23-31.
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6: Wang R, Ma Y, Zhan S, Zhang G, Cao L, Zhang X, Shi T, Chen W. B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expression Cell Death Dis. 2020 Jan 23;11(1):55.
7: Li L, Nian S, Liu Q, Zhang B, Jimu W, Li C, Huang Z, Hu Q, Huang Y, Yuan Q. Fully human anti-B7-H3 recombinant antibodies inhibited tumor growth by increasing T cell infiltration Int Immunopharmacol. 2024 May 10;132:111926.
8: Feng P, Zhang H, Zhang Z, Dai X, Mao T, Fan Y, Xie X, Wen H, Yu P, Hu Y, Yan R. The interaction of MMP-2/B7-H3 in human osteoporosis Clin Immunol. 2016 Jan;162:118-24.
9: Zhang C, Chen Y, Li F, Yang M, Meng F, Zhang Y, Chen W, Wang W. B7-H3 is spliced by SRSF3 in colorectal cancer Cancer Immunol Immunother. 2021 Feb;70(2):311-321.
10: Zhang GB, Chen YJ, Shi Q, Ma HB, Ge Y, Wang Q, Jiang Z, Xu Y, Zhang XG. Human recombinant B7-H3 expressed in E. coli enhances T lymphocyte proliferation and IL-10 secretion in vitro Acta Biochim Biophys Sin (Shanghai). 2004 Jun;36(6):430-6.

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