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Human FASR/TNFRSF6 (Recombinant)

$695.00 $495.00

Catalog Number: B2010358 (10 ug)
Human FASR/TNFRSF6 is a high quality research product used as highly pure Human FASR/TNFRSF6 expressed in HEK 293. This protein acts as a protein that belongs to the subgroup of the tumor necrosis factor receptor (TNF-R) family that can trigger apoptosis. Custom bulk orders of this product are available upon request.

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SKU: B2010358 Categories: , ,

Description

Human FASR/TNFRSF6
Catalog number: B2010358
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Human FASR/TNFRSF6 expressed in HEK 293. This protein acts as a protein that belongs to the subgroup of the tumor necrosis factor receptor (TNF-R) family that can trigger apoptosis.
Storage: -20C
Keywords: rHuFASR/TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Fas receptor; CD95; APT1; FAS1; Apo-1
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Mehrbod P, Ande SR, Alizadeh J, Rahimizadeh S, Shariati A, Malek H, Hashemi
M, Glover KKM, Sher AA, Coombs KM, Ghavami S. The roles of apoptosis, autophagy
and unfolded protein response in arbovirus, influenza virus, and HIV infections.
Virulence. 2019 Dec;10(1):376-413.

2: Mondino S, Vázquez CL, Cabruja M, Sala C, Cazenave-Gassiot A, Blanco FC, Wenk
MR, Bigi F, Cole ST, Gramajo H, Gago G. FasR Regulates Fatty Acid Biosynthesis
and Is Essential for Virulence of Mycobacterium tuberculosis. Front
Microbiol. 2020 Oct 27;11:586285.

3: Klatt C, Krüger I, Zey S, Krott KJ, Spelleken M, Gowert NS, Oberhuber A,
Pfaff L, Lückstädt W, Jurk K, Schaller M, Al-Hasani H, Schrader J, Massberg S,
Stark K, Schelzig H, Kelm M, Elvers M. Platelet-RBC interaction mediated by
FasL/FasR induces procoagulant activity important for thrombosis. J Clin Invest.
2018 Aug 31;128(9):3906-3925.

4: Sathaiah M, Thirunavukkarasu P, O’Malley ME, Kavanagh MA, Ravindranathan R,
Austin F, Guo ZS, Bartlett DL. Oncolytic poxvirus armed with Fas ligand leads to
induction of cellular Fas receptor and selective viral replication in FasR-
negative cancer. Cancer Gene Ther. 2012 Mar;19(3):192-201.

5: Wasiluk A, Ratomski K, Wnuczko K, Zak J, Szczepański M, Wysocka J, Jasińska
EA. Expression of FasR, Fas-L and Bcl-2 in CD4+ and CD8+ subpopulations of T
lymphocytes in the cord blood of healthy full-term newborns, is gender of
influence? Adv Med Sci. 2009;54(1):99-103.

6: Chen J, Zhang H, Su F, Min J, Zhang J, Song E. Cytokine associated
sensitivity of colon carcinoma cells to FasR-mediated cytotoxicity of CTL. Asian
J Surg. 2002 Jan;25(1):89-97.
7: Shadrin N, Shapira MG, Khalfin B, Uppalapati L, Parola AH, Nathan I. Serine
protease inhibitors interact with IFN-γ through up-regulation of FasR; a novel
therapeutic strategy against cancer. Exp Cell Res. 2015 Jan 15;330(2):233-239.
8: Keyser BM, Andres DK, Nealley E, Holmes WW, Benton B, Paradiso D, Appell A,
Carpin C, Anderson DR, Smith WJ, Ray R. Postexposure application of Fas receptor
small-interfering RNA to suppress sulfur mustard-induced apoptosis in human
airway epithelial cells: implication for a therapeutic approach. J Pharmacol Exp
Ther. 2013 Jan;344(1):308-16.

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