Human DiO-High Density Lipoprotein
Original price was: $1,595.00.$795.00Current price is: $795.00.
Catalog Number: B2027098 (0.5 mg)
Human DiO-High Density Lipoprotein is a fluorescently labeled lipoprotein complex designed for biotechnology and research applications to visualize HDL particle dynamics and lipid transport. It enables the tracking of selective lipid uptake and reverse cholesterol transport mechanisms by monitoring the transfer of lipids from the particle to target cell membranes. This product serves as an essential tool for studying cellular metabolism, lipid disorders, and receptor-mediated interactions without particle degradation. Custom bulk amounts of this product are available upon request.
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Product Description
Human DiO-High Density Lipoprotein
Catalog number: B2027098
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.5 mg
Molecular Weight or Concentration: NA
Supplied as: Solution
Storage: 2-8°C
Keywords: High density lipoprotein, HDL, fluorescently labeled HDL, human protein, lipid research, cellular uptake, scavenger receptor, endocytosis
References:
1. Goldstein, J. L., Ho, Y. K., Basu, S. K., & Brown, M. S. (1979). Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition. Proceedings of the National Academy of Sciences, 76(1), 333-337.
2. Pitas, R. E., Boyles, J., Mahley, R. W., & Bissell, D. M. (1985). Uptake of chemically modified low density lipoproteins in vivo is mediated by specific endothelial cells. Journal of Cell Cell Biology, 100(1), 103-117.
3. Kume, N., Arai, H., Kawai, C., & Kita, T. (1991). Receptors for modified low-density lipoproteins on human endothelial cells: different mechanisms for uptake of acetylated and oxidized low-density lipoproteins. Journal of Clinical Investigation, 88(3), 995-1002.
4. Tintut, Y., Patel, J., Parhami, F., & Demer, L. L. (2002). Acetylated low-density lipoprotein stimulates human vascular smooth muscle cell calcification by promoting osteoblastic differentiation and inhibiting phagocytosis. Circulation, 106(21), 2711-2717.
5. Brown, M. S., & Goldstein, J. L. (1983). Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. Annual Review of Biochemistry, 52, 223-261.
6. Krieger, M., & Herz, J. (1994). Structures and functions of scavenger receptors. Annual Review of Biochemistry, 63, 601-637.
7. Via, D. P., Dresel, H. A., Cheng, S. L., & Gotto, A. M. (1985). Murine macrophage scavenger receptor: in vivo expression and regulation as determined by anti-scavenger receptor monoclonal antibodies. Journal of Biological Chemistry, 260(12), 7379-7386.
8. Nagayama, M., Arai, H., Kita, T., & Oho, S. (1994). Differences in the metabolism of oxidatively modified low density lipoprotein and acetylated low density lipoprotein by human endothelial cells. Biochemical and Biophysical Research Communications, 202(1), 405-411.
9. Sparrow, C. P., Parthasarathy, S., & Steinberg, D. (1989). A macrophage receptor that recognizes oxidized low density lipoprotein but not acetylated low density lipoprotein. Journal of Biological Chemistry, 264(5), 2599-2604.
10. Lougheed, M., Moore, E. D., & Gase, J. C. (1997). Uptake and degradation of acetylated low density lipoprotein by human vascular endothelial cells via high-affinity binding. Arteriosclerosis, Thrombosis, and Vascular Biology, 17(4), 721-729.
Human DiO-High Density Lipoprotein
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Additional Information
| Weight | 0.15 oz |
|---|---|
| Dimensions | 2 × 0.5 × 0.5 in |
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