Human Chorionic Gonadotropin Alpha Subunit


Catalog Number: B2010654 (1 nmol)
Human Chorionic Gonadotropin Alpha Subunit is a highly pure lyophilised alpha subunit of human chorionic gonadotropin without hCG, alpha subunits or other beta forms. This product has been used as molecular tool in the research and development of hCG assays. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Human Chorionic Gonadotropin Alpha Subunit
Catalog number: B2010654
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 nmol
Molecular Weight or Concentration: na
Supplied as: Lyophilized
Applications: molecular tool in the research and development of hCG assays
Storage: -20C
Keywords: hCG Alpha Subunit, hCG, CG, hCG-α
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Fukayama M, Hayashi Y, Shiozawa Y, Okabe S, Koike M. Human chorionic
gonadotropin alpha-subunit in rectal carcinoids. Its mode of presence and the
change of granule morphology. Am J Pathol. 1989 Dec;135(6):1065-72.

2: Ren P, Sairam MR, Yarney TA. Bacterial expression of human chorionic
gonadotropin alpha subunit: studies on refolding, dimer assembly and interaction
with two different beta subunits. Mol Cell Endocrinol. 1995 Aug 30;113(1):39-51.

3: Benveniste R, Scommegha A. Human chorionic gonadotropin alpha-subunit in
pregnancy. Am J Obstet Gynecol. 1981 Dec 15;141(8):952-61.

4: Malhotra SS, Suman P, Gupta SK. Alpha or beta human chorionic gonadotropin
knockdown decrease BeWo cell fusion by down-regulating PKA and CREB activation.
Sci Rep. 2015 Jun 8;5:11210.

5: Kasai K, Kameya T, Kadoya K, Wada C. A pulmonary large cell carcinoma cell
line expressing neuroendocrine cell markers and human chorionic gonadotropin
alpha-subunit. Jpn J Cancer Res. 1991 Jan;82(1):12-8.

6: Bielinska M, Matzuk MM, Boime I. Site-specific processing of the N-linked
oligosaccharides of the human chorionic gonadotropin alpha_subunit. J Biol Chem.
1989 Oct 15;264(29):17113-8.

7: Posillico EG, Handwerger S, Tyrey L. Human chorionic gonadotropin alpha-
subunit of normal placenta: characterization of synthesis and association with
beta-subunit. Biol Reprod. 1985 Jun;32(5):1101-8.

8: Rouas N, Christophe S, Bellet D, Troalen F, Guillet JG, Bidart JM. Immune
recognition of a molecule naturally presented as a monomeric or an oligomeric
structure: the model of the human chorionic gonadotropin alpha subunit. Mol
Immunol. 1992 Jul-Aug;29(7-8):883-93.

9: Gupta R, Ezashi T, Roberts RM. Squelching of ETS2 transactivation by POU5F1
silences the human chorionic gonadotropin CGA subunit gene in human
choriocarcinoma and embryonic stem cells. Mol Endocrinol. 2012 May;26(5):859-72.
10: Arbiser JL, Arbiser ZK, Majzoub JA. Effects of hydroxyurea and cyclic
adenosine monophosphate/protein kinase A inhibitors on the expression of the
human chorionic gonadotropin alpha subunit and c-myc genes in choriocarcinoma. J
Endocrinol Invest. 1993 Dec;16(11):849-56.

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