Human BEX1 Protein

Description

Human BEX1 Protein
Catalog number: B2011602
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 20 µg
Molecular Weight or Concentration: 250 µg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Brain expressed protein, X-linked 1 protein, BEX2 protein, HBEX2 protein, HGR74-h protein, BEX1, BEX 1, BEX-1, BEX1 protein, BEX 1 protein, BEX-1 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Wang Q, Liang N, Yang T, Li Y, Li J, Huang Q, Wu C, Sun L, Zhou X, Cheng X, Zhao L, Wang G, Chen Z, He X, Liu C. DNMT1-mediated methylation of BEX1 regulates stemness and tumorigenicity in liver cancer J Hepatol. 2021 Nov;75(5):1142-1153.
2: Yang Y, Tetti M, Vohra T, Adolf C, Seissler J, Hristov M, Belavgeni A, Bidlingmaier M, Linkermann A, Mulatero P, Beuschlein F, Reincke M, Williams TA. BEX1 Is Differentially Expressed in Aldosterone-Producing Adenomas and Protects Human Adrenocortical Cells From Ferroptosis Hypertension. 2021 May 5;77(5):1647-1658.
3: Accornero F, Schips TG, Petrosino JM, Gu SQ, Kanisicak O, van Berlo JH, Molkentin JD. BEX1 is an RNA-dependent mediator of cardiomyopathy Nat Commun. 2017 Nov 30;8(1):1875.
4: Kazi JU, Kabir NN, Rönnstrand L. Brain-Expressed X-linked (BEX) proteins in human cancers Biochim Biophys Acta. 2015 Dec;1856(2):226-33.
5: Gu Y, Wei W, Cheng Y, Wan B, Ding X, Wang H, Zhang Y, Jin M. A pivotal role of BEX1 in liver progenitor cell expansion in mice Stem Cell Res Ther. 2018 Jun 15;9(1):164.
6: Xiao Q, Hu Y, Liu Y, Wang Z, Geng H, Hu L, Xu D, Wang K, Zheng L, Zheng S, Ding K. BEX1 promotes imatinib-induced apoptosis by binding to and antagonizing BCL-2 PLoS One. 2014 Mar 13;9(3):e91782.
7: Martens CR, Dorn LE, Kenney AD, Bansal SS, Yount JS, Accornero F. BEX1 is a critical determinant of viral myocarditis PLoS Pathog. 2022 Feb 22;18(2):e1010342.
8: Geng HT, Cheng ZW, Cao RJ, Wang ZB, Xing SZ, Guo C, Wang F, Liu CM, Chen SS, Cheng YF. Low expression of BEX1 predicts poor prognosis in patients with esophageal squamous cell cancer Oncol Rep. 2018 Nov;40(5):2778-2787.
9: Liu F, Huang W, Hong J, Cai C, Zhang W, Zhang J, Kang Z. Long noncoding RNA LINC00630 promotes radio-resistance by regulating BEX1 gene methylation in colorectal cancer cells IUBMB Life. 2020 Jul;72(7):1404-1414.
10: Lindblad O, Li T, Su X, Sun J, Kabir NN, Levander F, Zhao H, Lu G, Rönnstrand L, Kazi JU. BEX1 acts as a tumor suppressor in acute myeloid leukemia Oncotarget. 2015 Aug 28;6(25):21395-405.

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