Human Alix Protein

Product Description

Human Alix Protein
Catalog number: B2011583
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 1 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Alix protein (His tag), PDC6I protein, ALG2 interacting protein X protein, DRIP4 protein, KIAA1375 protein, Programmed cell death 6 interacting protein ALG 2 interacting protein 1 protein, HP95 protein, MGC17003 protein, Programmed cell death 6 interacting protein., AIP1 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Hoshino A, Kim HS, Bojmar L, Gyan KE, Cioffi M, Hernandez J, Zambirinis CP, Rodrigues G, Molina H, Heissel S, Mark MT, Steiner L, Benito-Martin A, Lucotti S, Di Giannatale A, Offer K, Nakajima M, Williams C, Nogués L, Pelissier Vatter FA, Hashimoto A, Davies AE, Freitas D, Kenific CM, Ararso Y, Buehring W, Lauritzen P, Ogitani Y, Sugiura K, Takahashi N, Alečković M, Bailey KA, Jolissant JS, Wang H, Harris A, Schaeffer LM, García-Santos G, Posner Z, Balachandran VP, Khakoo Y, Raju GP, Scherz A, Sagi I, Scherz-Shouval R, Yarden Y, Oren M, Malladi M, Petriccione M, De Braganca KC, Donzelli M, Fischer C, Vitolano S, Wright GP, Ganshaw L, Marrano M, Ahmed A, DeStefano J, Danzer E, Roehrl MHA, Lacayo NJ, Vincent TC, Weiser MR, Brady MS, Meyers PA, Wexler LH, Ambati SR, Chou AJ, Slotkin EK, Modak S, Roberts SS, Basu EM, Diolaiti D, Krantz BA, Cardoso F, Simpson AL, Berger M, Rudin CM, Simeone DM, Jain M, Ghajar CM, Batra SK, Stanger BZ, Bui J, Brown KA, Rajasekhar VK, Healey JH, de Sousa M, Kramer K, Sheth S, Baisch J, Pascual V, Heaton TE, La Quaglia MP, Pisapia DJ, Schwartz R, Zhang H, Liu Y, Shukla A, Blavier L, DeClerck YA, et al. Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers Cell. 2020 Aug 20;182(4):1044-1061.e18.
2: Larios J, Mercier V, Roux A, Gruenberg J. ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes J Cell Biol. 2020 Mar 2;219(3):e201904113.
3: Baietti MF, Zhang Z, Mortier E, Melchior A, Degeest G, Geeraerts A, Ivarsson Y, Depoortere F, Coomans C, Vermeiren E, Zimmermann P, David G. Syndecan-syntenin-ALIX regulates the biogenesis of exosomes Nat Cell Biol. 2012 Jun 3;14(7):677-85.
4: Toh WS, Lai RC, Zhang B, Lim SK. MSC exosome works through a protein-based mechanism of action Biochem Soc Trans. 2018 Aug 20;46(4):843-853.
5: Sun R, Liu Y, Lu M, Ding Q, Wang P, Zhang H, Tian X, Lu P, Meng D, Sun N, Xiang M, Chen S. ALIX increases protein content and protective function of iPSC-derived exosomes J Mol Med (Berl). 2019 Jun;97(6):829-844.
6: Zhao F, Kim W, Gao H, Liu C, Zhang Y, Chen Y, Deng M, Zhou Q, Huang J, Hu Q, Chen SH, Nowsheen S, Kloeber JA, Qin B, Yin P, Tu X, Guo G, Qin S, Zhang C, Gao M, Luo K, Liu Y, Lou Z, Yuan J. ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection Nat Cell Biol. 2021 Aug;23(8):894-904.
7: Shi A, Li J, Qiu X, Sabbah M, Boroumand S, Huang TC, Zhao C, Terzic A, Behfar A, Moran SL. TGF-β loaded exosome enhances ischemic wound healing in vitro and in vivo Theranostics. 2021 Apr 30;11(13):6616-6631.
8: Fabbiano F, Corsi J, Gurrieri E, Trevisan C, Notarangelo M, D’Agostino VG. RNA packaging into extracellular vesicles: An orchestra of RNA-binding proteins? J Extracell Vesicles. 2020 Dec;10(2):e12043.
9: Jia J, Claude-Taupin A, Gu Y, Choi SW, Peters R, Bissa B, Mudd MH, Allers L, Pallikkuth S, Lidke KA, Salemi M, Phinney B, Mari M, Reggiori F, Deretic V. Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal Dev Cell. 2020 Jan 6;52(1):69-87.e8.
10: Zhao C, Ban N, Dai S, Zhang X, Zhang L, Xu P, Chen W, Sun J, Bao Z, Chang H, Wang D, Ren J. The role of Alix in the proliferation of human glioma cells Hum Pathol. 2016 Jun;52:110-8.

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