Human Aldose Reductase Protein

Description

Human Aldose Reductase Protein
Catalog number: B2011582
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 1 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Aldose reductase protein, ALR2 protein, member B1 AKR1B 1 protein, ALDR1 protein, aldehyde reductase 1 protein, aldo-keto reductase family 1 protein, AKR1B1 protein, Aldo-keto reductase family1 member B1 protein, AR protein, aldr-1 protein, Lii5-2 CTCL tumor protein , ADR p
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Pal PB, Sonowal H, Shukla K, Srivastava SK, Ramana KV. Aldose reductase regulates hyperglycemia-induced HUVEC death via SIRT1/AMPK-α1/mTOR pathway J Mol Endocrinol. 2019 Jul 1;63(1):11-25.
2: Sekhon G, Singh R. Human aldose reductase unfolds through an intermediate F1000Res. 2019 Apr 26;8:564.
3: Quattrini L, La Motta C. Aldose reductase inhibitors: 2013-present Expert Opin Ther Pat. 2019 Mar;29(3):199-213.
4: Kousaxidis A, Petrou A, Lavrentaki V, Fesatidou M, Nicolaou I, Geronikaki A. Aldose reductase and protein tyrosine phosphatase 1B inhibitors as a promising therapeutic approach for diabetes mellitus Eur J Med Chem. 2020 Dec 1;207:112742.
5: Obrosova IG, Kador PF. Aldose reductase / polyol inhibitors for diabetic retinopathy Curr Pharm Biotechnol. 2011 Mar 1;12(3):373-85.
6: Balestri F, Poli G, Pineschi C, Moschini R, Cappiello M, Mura U, Tuccinardi T, Del Corso A. Aldose Reductase Differential Inhibitors in Green Tea Biomolecules. 2020 Jul 6;10(7):1003.
7: Mohd Siddique MU, Thakur A, Shilkar D, Yasmin S, Halakova D, Kovacikova L, Prnova MS, Stefek M, Acevedo O, Dasararaju G, Devadasan V, Mondal SK, Jayaprakash V. Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives Eur J Med Chem. 2021 Nov 5;223:113630.
8: Cho SB, Eum WS, Shin MJ, Yeo HJ, Yeo EJ, Choi YJ, Kwon HJ, Cho SW, Park J, Han KH, Lee KW, Park JK, Kim DS, Kim DW, Choi SY. Tat‑aldose reductase prevents dopaminergic neuronal cell death by inhibiting oxidative stress and MAPK activation Int J Mol Med. 2021 Feb;47(2):751-760.
9: Petrovič D. Aldose reductase, glucose and cataracts J Diabetes Complications. 2014 Mar-Apr;28(2):120-1.
10: Sarikaya M, Yazihan N, Daş Evcimen N. Relationship between aldose reductase enzyme and the signaling pathway of protein kinase C in an in vitro diabetic retinopathy model Can J Physiol Pharmacol. 2020 Apr;98(4):243-251.

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