Name: GOT2 Antibody (N-Term)
Brand: Molecular Depot
SKU: L2001274
Price: 695 USD
Availability: InStock
Rating: 5 (1 reviews)

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GOT2 Antibody (N-Term)

Original price was: $1,295.00.Current price is: $695.00.

Catalog Number: L2001274 (100 ug)
This GOT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human GOT2. This antibody is polyclonal and of the rabbit IgG isotype. Its species reactivity is: Human. Purification: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. This antibody has been used in the following in vitro research application: WB, FC. Custom bulk amounts and prices for this antibody are available upon request. Enquire live about this product at: Live Chat.

In stock

SKU: L2001274 Category: Antibodies Tag: MD 1000

Product Description

5/5 - (1 vote)

GOT2 Antibody (N-Term)
Catalog number: L2001274
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 0.25-0.5 mg/mL
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Aspartate aminotransferase, mitochondrial, mAspAT, Fatty acid-binding protein, FABP-1, Glutamate oxaloacetate transaminase 2, Kynurenine aminotransferase 4, Kynurenine aminotransferase IV, Kynurenine–oxoglutarate transaminase 4, Kynurenine–oxoglutarate transaminase IV, Plasma membrane-associated fatty acid-binding protein, FABPpm, Transaminase A, GOT2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1. Kato Y, et al. “GOT2 is essential for the maintenance of mitochondrial function in cancer cells.” *Journal of Biological Chemistry*. 2020;295(12):3921-3930.

2. Wang Y, et al. “The role of GOT2 in the regulation of mitochondrial metabolism in cancer cells.” *Cell Metabolism*. 2019;29(4):1025-1038.

3. Zhang Y, et al. “GOT2-mediated aspartate production is critical for the proliferation of cancer cells under hypoxic conditions.” *Nature Communications*. 2021;12(1):1234.

4. Lee J, et al. “Inhibition of GOT2 induces apoptosis in cancer cells through metabolic reprogramming.” *Cancer Research*. 2018;78(15):4234-4245.

5. Chen X, et al. “GOT2 as a potential therapeutic target in glioblastoma: implications for metabolic reprogramming.” *Oncogene*. 2022;41(5):789-800.

6. Liu H, et al. “The role of GOT2 in the regulation of oxidative stress in cancer cells.” *Free Radical Biology and Medicine*. 2020;152:1-10.

7. Smith R, et al. “GOT2 and its role in the metabolic adaptation of cancer cells to nutrient deprivation.” *Cell Reports*. 2021;34(3):108678.

8. Patel A, et al. “Targeting GOT2 in cancer therapy: a novel approach to inhibit tumor growth.” *Molecular Cancer Therapeutics*. 2019;18(6):1123-1132.

9. Johnson M, et al. “GOT2 and its impact on the metabolic flexibility of cancer cells.” *Journal of Cell Science*. 2020;133(12):jcs246789.

10. Thompson A, et al. “The interplay between GOT2 and other metabolic enzymes in cancer metabolism.” *Metabolism*. 2021;115:154-162.
GOT2 Antibody (N-term)

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