CYFRA 21-1 Human Antigen


Catalog Number: B2010543 (10 ug)
CYFRA 21-1 Human Antigen is a highly pure (> 95% by SDS page) member of the type I keratin family. This product has been used as marker for the detection of tumor cells in lymph nodes and other locations. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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CYFRA 21-1 Human Antigen
Catalog number: B2010543
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: na
Supplied as: Solution
Applications: marker for the detection of tumor cells in lymph nodes and other locations
Storage: −20°C
Keywords: cytokeratin 19 fragment, Cytokeratin 19, Keratin 19, CK-19, K19, Type I Cytoskeletal 19, Cyfra 21-1, Keratin, type I cytoskeletal 19
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Cho HY, Kyung MS. CYFRA 21-1 and Placental Growth Factor as Screening Markers
for Endometriosis. Med Sci Monit. 2019 Feb 9;25:1087-1092.

2: Hyun JW, Shin HS, Kim SH, Kong SY, Yoo H, Gwak HS, Kim HJ. CYFRA 21-1 levels
in cerebrospinal fluid as a putative therapeutic monitoring biomarker for
patients with leptomeningeal carcinomatosis: A pilot study. Cancer Biomark.

3: Rudhart SA, Schultz JD, Gehrt F, Pavel FL, Birk R, Hoch M, Stuck BA, Hoch S.
CYFRA 21-1: a suitable tumor marker in patients with head and neck cutaneous
squamous cell carcinoma? Eur Arch Otorhinolaryngol. 2019 Dec;276(12):3467-3475.

4: Rudhart SA, Gehrt F, Birk R, Schultz JD, Stankovic P, Georgiew R, Wilhelm T,
Stuck BA, Hoch S. Clinical relevance of CYFRA 21-1 as a tumour marker in
patients with oropharyngeal squamous cell carcinoma. Eur Arch Otorhinolaryngol.
2020 Sep;277(9):2561-2571.

5: Shirasu H, Ono A, Omae K, Nakashima K, Omori S, Wakuda K, Kenmotsu H, Naito
T, Murakami H, Endo M, Nakajima T, Takahashi T. CYFRA 21-1 predicts the efficacy
of nivolumab in patients with advanced lung adenocarcinoma. Tumour Biol. 2018

6: AlAli AM, Walsh T, Maranzano M. CYFRA 21-1 and MMP-9 as salivary biomarkers
for the detection of oral squamous cell carcinoma: a systematic review of
diagnostic test accuracy. Int J Oral Maxillofac Surg. 2020 Aug;49(8):973-983.

7: Matuszczak M, Salagierski M. Diagnostic and Prognostic Potential of
Biomarkers CYFRA 21.1, ERCC1, p53, FGFR3 and TATI in Bladder Cancers. Int J Mol
Sci. 2020 May 9;21(9):3360.

8: Huang YL, Chen J, Yan W, Zang D, Qin Q, Deng AM. Diagnostic accuracy of
cytokeratin-19 fragment (CYFRA 21-1) for bladder cancer: a systematic review and
meta-analysis. Tumour Biol. 2015 May;36(5):3137-45.

9: Vercauteren IM, Verleden SE, McDonough JE, Vandermeulen E, Ruttens D,
Lammertyn EJ, Bellon H, De Dycker E, Dooms C, Yserbyt J, Verleden GM,
Vanaudenaerde BM, Wuyts WA. CYFRA 21.1 in bronchoalveolar lavage of idiopathic
pulmonary fibrosis patients. Exp Lung Res. 2015;41(8):459-65.
10: Lin Q, Chen XY, Liu WF, Zhu PW, Shi WQ, Li B, Yuan Q, Min YL, Liu JM, Shao
Y. Diagnostic value of CA-153 and CYFRA 21-1 in predicting intraocular
metastasis in patients with metastatic lung cancer. Cancer Med. 2020

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