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CD40 Ligand (Human, Recombinant)

$695.00 $495.00

Catalog Number: B2010347 (10 ug)
CD40 Ligand (Human, Recombinant) is a high quality research product used as highly pure CD40 Ligand (Human, Recombinant) expressed in E. coli. This protein acts as an important role in immune system regulation, including myeloid progenitor cell development. Custom bulk orders of this product are available upon request.

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SKU: B2010347 Categories: , ,

Description

CD40 Ligand (Human, Recombinant)
Catalog number: B2010347
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure CD40 Ligand (Human, Recombinant) expressed in E. coli. This protein acts as an important role in immune system regulation, including myeloid progenitor cell development.
Storage: -20C
Keywords: rHuCD40L; CD154; TRAP; TNFSF5; CD40LG; CD40-L
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Kuhn NF, Purdon TJ, van Leeuwen DG, Lopez AV, Curran KJ, Daniyan AF,
Brentjens RJ. CD40_Ligand-Modified Chimeric Antigen Receptor T Cells Enhance
Antitumor Function by Eliciting an Endogenous Antitumor Response. Cancer Cell.
2019 Mar 18;35(3):473-488.e6.

2: Karnell JL, Rieder SA, Ettinger R, Kolbeck R. Targeting the CD40-CD40L
pathway in autoimmune diseases: Humoral immunity and beyond. Adv Drug Deliv Rev.
2019 Feb 15;141:92-103.

3: Kawabe T, Matsushima M, Hashimoto N, Imaizumi K, Hasegawa Y. CD40/CD40_ligand
interactions in immune responses and pulmonary immunity. Nagoya J Med Sci. 2011
Aug;73(3-4):69-78.

4: Rizvi M, Pathak D, Freedman JE, Chakrabarti S. CD40-CD40_ligand interactions
in oxidative stress, inflammation and vascular disease. Trends Mol Med. 2008
Dec;14(12):530-8.

5: Meng X, Yang B, Suen WC. Prospects for modulating the CD40/CD40L pathway in
the therapy of the hyper-IgM syndrome. Innate Immun. 2018 Jan;24(1):4-10.

6: Antoniades C, Bakogiannis C, Tousoulis D, Antonopoulos AS, Stefanadis C. The
CD40/CD40 ligand system: linking inflammation with atherothrombosis. J Am Coll
Cardiol. 2009 Aug 18;54(8):669-77.

7: Danese S, Fiocchi C. Platelet activation and the CD40/CD40 ligand pathway:
mechanisms and implications for human disease. Crit Rev Immunol.
2005;25(2):103-21.

8: Schönbeck U, Libby P. The CD40/CD154 receptor/ligand dyad. Cell Mol Life Sci.
2001 Jan;58(1):4-43.
9: Sahler J, Spinelli S, Phipps R, Blumberg N. CD40 ligand (CD154) involvement
in platelet transfusion reactions. Transfus Clin Biol. 2012 Jun;19(3):98-103.

Products Related to CD40 Ligand (Human, Recombinant) : Proteins

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