Beta Defensin-4 (Human, Recombinant)

Description

Beta Defensin-4 (Human, Recombinant)
Catalog number: B2010346
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Beta Defensin-4 (Human, Recombinant) expressed in E. coli. This protein acts as an inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity.
Storage: -20C
Keywords: rHuBD-4; DEFB-4; Beta-defensin 104; DEFB4; DEFB104
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Zhai Y, Yuan X, Zhao Y, Ge L, Wang Y. Potential Application of Human
β-Defensin 4 in Dental Pulp Repair. Front Physiol. 2020 Aug 21;11:1077.

2: Prahl A, Pazgier M, Alexandratos J, Lubkowski J. Human β-defensin 4 –
defensin without the “twist”. Postepy Biochem. 2016;62(3):349-361.

3: Musumeci G, Carnazza ML, Loreto C, Leonardi R, Loreto C. β-Defensin-4 (HBD-4)
is expressed in chondrocytes derived from normal and osteoarthritic cartilage
encapsulated in PEGDA scaffold. Acta Histochem. 2012 Dec;114(8):805-12.

4: Brodowska P, Zwierzchowski L, Marczak S, Jarmuż W, Bagnicka E. Associations
between Bovine β-Defensin 4 Genotypes and Production Traits of Polish Holstein-
Friesian Dairy Cattle. Animals (Basel). 2019 Sep 25;9(10):723.

5: Noda-Nicolau NM, Bastos LB, Bolpetti AN, Pinto GVS, Marcolino LD, Marconi C,
Ferreira CST, Polettini J, Vieira EP, da Silva MG. Cervicovaginal Levels of
Human β-Defensin 1, 2, 3, and 4 of Reproductive-Aged Women With Chlamydia
trachomatis Infection. J Low Genit Tract Dis. 2017 Jul;21(3):189-192.

6: Leung K. ^99mTc-Human β-defensin-3. 2009 Aug 25 [updated 2009 Nov
19]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet].
Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013.

7: Zhai Y, Wang Y, Rao N, Li J, Li X, Fang T, Zhao Y, Ge L. Activation and
Biological Properties of Human β Defensin 4 in Stem Cells Derived From Human
Exfoliated Deciduous Teeth. Front Physiol. 2019 Oct 22;10:1304.

8: Musumeci G, Carnazza ML, Leonardi R, Loreto C. Expression of β-defensin-4 in
“an in vivo and ex vivo model” of human osteoarthritic knee meniscus. Knee Surg
Sports Traumatol Arthrosc. 2012 Feb;20(2):216-22.

9: Gerashchenko OL, Zhuravel EV, Skachkova OV, Khranovska NN, Filonenko VV,
Pogrebnoy PV, Soldatkina MA. Biologic activities of recombinant human-beta-
defensin-4 toward cultured human cancer cells. Exp Oncol. 2013 Jun;35(2):76-82.

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