Anti-Trap1 Antibody Conjugated to FITC

Product Description

Anti-Trap1 Antibody Conjugated to FITC
Catalog number: B2016791
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 75 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: Anti-Heat shock protein 75, Anti-Hsp75, Anti-Hsp90L, Anti-TNFR associated protein 1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Vural B, ÇaliŞkan M, SezgİntÜrk MK. Development of a biosensor platform based on ITO sheets modified with 3-glycidoxypropyltrimethoxysilane for early detection of TRAP1 Turk J Chem. 2020 Apr 1;44(2):461-471.
2: Wang R, Shao F, Liu Z, Zhang J, Wang S, Liu J, Liu H, Chen H, Liu K, Xia M, Wang Y. The Hsp90 inhibitor SNX-2112, induces apoptosis in multidrug resistant K562/ADR cells through suppression of Akt/NF-κB and disruption of mitochondria-dependent pathways Chem Biol Interact. 2013 Sep 5;205(1):1-10.
3: Kim D, Kim SY, Kim D, Yoon NG, Yun J, Hong KB, Lee C, Lee JH, Kang BH, Kang S. Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models Bioorg Chem. 2020 Aug;101:103901.
4: Zhang Y, Miao Y, Tan J, Chen F, Lei P, Zhang Q. Identification of mitochondrial related signature associated with immune microenvironment in Alzheimer’s disease J Transl Med. 2023 Jul 11;21(1):458.
5: Kim SY, Yoon NG, Im JY, Lee JH, Kim J, Jeon Y, Choi YJ, Lee JH, Uemura A, Park DH, Kang BH. Targeting the Mitochondrial Chaperone TRAP1 Alleviates Vascular Pathologies in Ischemic Retinopathy Adv Sci (Weinh). 2024 Jan;11(2):e2302776.
6: Yang S, Yoon NG, Park MA, Yun J, Im JY, Kang BH, Kang S. Triphenylphosphonium conjugation to a TRAP1 inhibitor, 2-amino-6-chloro-7,9-dihydro-8H-purin-8-one increases antiproliferative activity Bioorg Chem. 2022 Sep;126:105856.
7: Yoshida S, Tsutsumi S, Muhlebach G, Sourbier C, Lee MJ, Lee S, Vartholomaiou E, Tatokoro M, Beebe K, Miyajima N, Mohney RP, Chen Y, Hasumi H, Xu W, Fukushima H, Nakamura K, Koga F, Kihara K, Trepel J, Picard D, Neckers L. Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):E1604-12.
8: Sun W, Wen M, Liu M, Wang Q, Liu Q, Li L, Siebert HC, Loers G, Zhang R, Zhang N. Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model Front Aging Neurosci. 2022 Dec 1;14:1075161.
9: Im CN, Seo JS. Overexpression of tumor necrosis factor receptor-associated protein 1 (TRAP1), leads to mitochondrial aberrations in mouse fibroblast NIH/3T3 cells BMB Rep. 2014 May;47(5):280-5.
10: Hu G, Bakkeren E, Caza M, Horianopoulos L, Sánchez-León E, Sorensen M, Jung W, Kronstad JW. Vam6/Vps39/TRAP1-domain proteins influence vacuolar morphology, iron acquisition and virulence in Cryptococcus neoformans Cell Microbiol. 2021 Dec;23(12):e13400.

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