7-Aminoactinomycin D (7-AAD)
Catalog Number: B2011284 (1 mg)
7-Aminoactinomycin D (7-AAD) is a high quality DNA strain. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
Live enquiry about this product via Text/SMS: 1-858-900-3210.
7-Aminoactinomycin D (7-AAD)
Catalog number: B2011284
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1270.5 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: 7 Aminoactinomycin D
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
1: Zembruski NC, Stache V, Haefeli WE, Weiss J. 7-Aminoactinomycin D for apoptosis staining in flow cytometry Anal Biochem. 2012 Oct 1;429(1):79-81.
2: Zhang X, Zhang P, An L, Sun N, Peng L, Tang W, Ma D, Chen J. Miltirone induces cell death in hepatocellular carcinoma cell through GSDME-dependent pyroptosis Acta Pharm Sin B. 2020 Aug;10(8):1397-1413.
3: Wu H, Liu C, Yang Q, Xin C, Du J, Sun F, Zhou L. MIR145-3p promotes autophagy and enhances bortezomib sensitivity in multiple myeloma by targeting HDAC4 Autophagy. 2020 Apr;16(4):683-697.
4: Wadkins RM, Jovin TM. Actinomycin D and 7-aminoactinomycin D binding to single-stranded DNA Biochemistry. 1991 Oct 1;30(39):9469-78.
5: Liu J, Yang X, Wang H, Li Z, Deng H, Liu J, Xiong S, He J, Feng X, Guo C, Wang W, Zelinskyy G, Trilling M, Sutter K, Senff T, Menne C, Timm J, Zhang Y, Deng F, Lu Y, Wu J, Lu M, Yang D, Dittmer U, Wang B, Zheng X. Analysis of the Long-Term Impact on Cellular Immunity in COVID-19-Recovered Individuals Reveals a Profound NKT Cell Impairment mBio. 2021 Apr 27;12(2):e00085-21.
6: Chen D, Eyupoglu IY, Savaskan N. Ferroptosis and Cell Death Analysis by Flow Cytometry Methods Mol Biol. 2017;1601:71-77.
7: Fleetwood AJ, Lee MKS, Singleton W, Achuthan A, Lee MC, O’Brien-Simpson NM, Cook AD, Murphy AJ, Dashper SG, Reynolds EC, Hamilton JA. Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles Front Cell Infect Microbiol. 2017 Aug 4;7:351.
8: Loborg H, Lindén E, Lönn A, Skoglund P, Rundquist I. High affinity binding of 7-aminoactinomycin D and 4′,6-diamidino-2-phenylindole to human neutrophilic granulocytes and lymphocytes Cytometry. 1995 Aug 1;20(4):296-306.
9: Lindén E, Skoglund P, Rundquist I. Accessibility of 7-aminoactinomycin D to lymphocyte nuclei after paraformaldehyde fixation Cytometry. 1997 Jan 1;27(1):92-5.
10: Lecoeur H, de Oliveira-Pinto LM, Gougeon ML. Multiparametric flow cytometric analysis of biochemical and functional events associated with apoptosis and oncosis using the 7-aminoactinomycin D assay J Immunol Methods. 2002 Jul 1;265(1-2):81-96.
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