7-Aminoactinomycin D (7-AAD)

Product Description

7-Aminoactinomycin D (7-AAD)
Catalog number: B2011284
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1270.5 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: 7 Aminoactinomycin D
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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4: Wadkins RM, Jovin TM. Actinomycin D and 7-aminoactinomycin D binding to single-stranded DNA Biochemistry. 1991 Oct 1;30(39):9469-78.
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6: Chen D, Eyupoglu IY, Savaskan N. Ferroptosis and Cell Death Analysis by Flow Cytometry Methods Mol Biol. 2017;1601:71-77.
7: Fleetwood AJ, Lee MKS, Singleton W, Achuthan A, Lee MC, O’Brien-Simpson NM, Cook AD, Murphy AJ, Dashper SG, Reynolds EC, Hamilton JA. Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles Front Cell Infect Microbiol. 2017 Aug 4;7:351.
8: Loborg H, Lindén E, Lönn A, Skoglund P, Rundquist I. High affinity binding of 7-aminoactinomycin D and 4′,6-diamidino-2-phenylindole to human neutrophilic granulocytes and lymphocytes Cytometry. 1995 Aug 1;20(4):296-306.
9: Lindén E, Skoglund P, Rundquist I. Accessibility of 7-aminoactinomycin D to lymphocyte nuclei after paraformaldehyde fixation Cytometry. 1997 Jan 1;27(1):92-5.
10: Lecoeur H, de Oliveira-Pinto LM, Gougeon ML. Multiparametric flow cytometric analysis of biochemical and functional events associated with apoptosis and oncosis using the 7-aminoactinomycin D assay J Immunol Methods. 2002 Jul 1;265(1-2):81-96.

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