Troponin I (Recombinant)

Description

Troponin I (Recombinant)
Catalog number: B2013916
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: 24 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Troponin I (Recombinant)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Tajbakhsh A, Gheibi Hayat SM, Taghizadeh H, Akbari A, Inabadi M, Savardashtaki A, Johnston TP, Sahebkar A. COVID-19 and cardiac injury: clinical manifestations, biomarkers, mechanisms, diagnosis, treatment, and follow up Expert Rev Anti Infect Ther. 2021 Mar;19(3):345-357.
2: Luan HH, Wang A, Hilliard BK, Carvalho F, Rosen CE, Ahasic AM, Herzog EL, Kang I, Pisani MA, Yu S, Zhang C, Ring AM, Young LH, Medzhitov R. GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance Cell. 2019 Aug 22;178(5):1231-1244.e11.
3: Guzik TJ, Mohiddin SA, Dimarco A, Patel V, Savvatis K, Marelli-Berg FM, Madhur MS, Tomaszewski M, Maffia P, D’Acquisto F, Nicklin SA, Marian AJ, Nosalski R, Murray EC, Guzik B, Berry C, Touyz RM, Kreutz R, Wang DW, Bhella D, Sagliocco O, Crea F, Thomson EC, McInnes IB. COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options Cardiovasc Res. 2020 Aug 1;116(10):1666-1687.
4: Altshuler EP, Vylegzhanina AV, Katrukha IA, Bereznikova AV, Serebryanaya DV. Application of recombinant antibody fragments for troponin I measurements Biochemistry (Mosc). 2012 Dec;77(12):1362-7.
5: Hyyti_ H, Heikkil_ T, Brockmann EC, Kekki H, Hedberg P, Puolakanaho T, Lvgren T, Pettersson K. Chimeric recombinant antibody fragments in cardiac troponin I immunoassay Clin Biochem. 2015 Mar;48(4-5):347-52.
6: Strauss JD, Van Eyk JE, Barth Z, Kluwe L, Wiesner RJ, Mada K, R_egg JC. Recombinant troponin I substitution and calcium responsiveness in skinned cardiac muscle Pflugers Arch. 1996 Apr;431(6):853-62.
7: Liu S, Zhang MY, Song Q, Ling M, Kadijevic L, Shi Q. Recombinant single chain cardiac troponin I-C polypeptides: superior calibration and control materials for cardiac troponin I immunoassays Clin Lab. 2001;47(1-2):19-27.
8: Yan C, Sack JS. X-ray structure of a human cardiac muscle troponin C/troponin I chimera in two crystal forms Acta Crystallogr F Struct Biol Commun. 2022 Jan 1;78(Pt 1):17-24.
9: Huang X, Pi Y, Lee KJ, Henkel AS, Gregg RG, Powers PA, Walker JW. Cardiac troponin I gene knockout: a mouse model of myocardial troponin I deficiency Circ Res. 1999 Jan 8-22;84(1):1-8.
10: Wang ZY, Sarkar S, Gergely J, Tao T. Ca2(+)-dependent interactions between the C-helix of troponin-C and troponin-I. Photocross-linking and fluorescence studies using a recombinant troponin-C J Biol Chem. 1990 Mar 25;265(9):4953-7.

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