Tau – 441 Conjugated to Biotin

Description

Tau – 441 Conjugated to Biotin
Catalog number: B2011339
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 71.8 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -80 °C
Keywords: Biotinylated Tau-441
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Ahmad W Dr, Shabbiri K Dr, Ahmad I. Prediction of human tau 3D structure, and interplay between O-β-GlcNAc and phosphorylation modifications in Alzheimer’s disease: C. elegans as a suitable model to study these interactions in vivo Biochem Biophys Res Commun. 2020 Jul 30;528(3):466-472.
2: Sandhu P, Naeem MM, Lu C, Kumarathasan P, Gomes J, Basak A. Ser(422) phosphorylation blocks human Tau cleavage by caspase-3: Biochemical implications to Alzheimer’s Disease Bioorg Med Chem Lett. 2017 Feb 1;27(3):642-652.
3: Kitano-Takahashi M, Morita H, Kondo S, Tomizawa K, Kato R, Tanio M, Shirota Y, Takahashi H, Sugio S, Kohno T. Expression, purification and crystallization of a human tau-tubulin kinase 2 that phosphorylates tau protein Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jul 1;63(Pt 7):602-4.
4: Banks WA, Kovac A, Majerova P, Bullock KM, Shi M, Zhang J. Tau Proteins Cross the Blood-Brain Barrier J Alzheimers Dis. 2017;55(1):411-419.
5: Goedert M, Jakes R. Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization EMBO J. 1990 Dec;9(13):4225-30.
6: Shimonaka S, Matsumoto SE, Elahi M, Ishiguro K, Hasegawa M, Hattori N, Motoi Y. Asparagine residue 368 is involved in Alzheimer’s disease tau strain-specific aggregation J Biol Chem. 2020 Oct 9;295(41):13996-14014.
7: Landrieu I, Leroy A, Smet-Nocca C, Huvent I, Amniai L, Hamdane M, Sibille N, Buée L, Wieruszeski JM, Lippens G. NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer’s disease Biochem Soc Trans. 2010 Aug;38(4):1006-11.
8: Karikari TK, Keeling S, Hill E, Lantero Rodrı Guez J, Nagel DA, Becker B, Höglund K, Zetterberg H, Blennow K, Hill EJ, Moffat KG. Extensive Plasmid Library to Prepare Tau Protein Variants and Study Their Functional Biochemistry ACS Chem Neurosci. 2020 Oct 7;11(19):3117-3129.
9: Miller ML, Johnson GV. Transglutaminase cross-linking of the tau protein J Neurochem. 1995 Oct;65(4):1760-70.
10: Townsend D, Fullwood NJ, Yates EA, Middleton DA. Aggregation Kinetics and Filament Structure of a Tau Fragment Are Influenced by the Sulfation Pattern of the Cofactor Heparin Biochemistry. 2020 Oct 20;59(41):4003-4014.

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