Tamm Horsfall Glycoprotein
Original price was: $2,995.00.$1,595.00Current price is: $1,595.00.
Catalog Number: B2013459 (0.5 mg)
Tamm Horsfall Glycoprotein is native Tamm Horsfall glycoprotein purified from human urine. This protein also known as uromodulin, is a high-molecular-weight (85-100 kDa) glycoprotein primarily synthesized by the renal epithelial cells in the thick ascending limb of the loop of Henle. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
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Product Description
Tamm Horsfall Glycoprotein
Catalog number: B2013459
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.5 mg
Molecular Weight or Concentration: ~100 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Tamm Horsfall Glycoprotein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Bleyer AJ, Kmoch S. Tamm_Horsfall Glycoprotein and Uromodulin: It Is All about the Tubules! Clin J Am Soc Nephrol. 2016 Jan 7;11(1):6-8.
2: Serafini-Cessi F, Malagolini N, Cavallone D. Tamm-Horsfall glycoprotein: biology and clinical relevance Am J Kidney Dis. 2003 Oct;42(4):658-76.
3: Hess B. Tamm_Horsfall glycoprotein–inhibitor or promoter of calcium oxalate monohydrate crystallization processes? Urol Res. 1992;20(1):83-6.
4: Hess B. Tamm_Horsfall glycoprotein and calcium nephrolithiasis Miner Electrolyte Metab. 1994;20(6):393-8.
5: Hess B. The role of Tamm_Horsfall glycoprotein and Nephrocalcin in calcium oxalate monohydrate crystallization processes Scanning Microsc. 1991 Sep;5(3):689-95; discussion 696.
6: Pressac M. [Tamm-Horsfall protein] Ann Biol Clin (Paris). 2000 Mar-Apr;58(2):167-76.
7: Serafini-Cessi F, Monti A, Cavallone D. N-Glycans carried by Tamm_Horsfall glycoprotein have a crucial role in the defense against urinary tract diseases Glycoconj J. 2005 Nov;22(7-9):383-94.
8: Kumar S, Muchmore A. Tamm_Horsfall protein–uromodulin (1950-1990) Kidney Int. 1990 Jun;37(6):1395-401.
9: Eckardt KU, Alper SL, Antignac C, Bleyer AJ, Chauveau D, Dahan K, Deltas C, Hosking A, Kmoch S, Rampoldi L, Wiesener M, Wolf MT, Devuyst O; Kidney Disease: Improving Global Outcomes. Autosomal dominant tubulointerstitial kidney disease: diagnosis, classification, and management–A KDIGO consensus report Kidney Int. 2015 Oct;88(4):676-83.
10: Patras KA, Coady A, Olson J, Ali SR, RamachandraRao SP, Kumar S, Varki A, Nizet V. Tamm-Horsfall glycoprotein engages human Siglec-9 to modulate neutrophil activation in the urinary tract Immunol Cell Biol. 2017 Nov;95(10):960-965.
Products Related to Tamm Horsfall Glycoprotein can be found at Proteins
Additional Information
| Weight | 0.15 oz |
|---|---|
| Dimensions | 2 × 0.5 × 0.5 in |
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