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SARS-CoV-2 Spike S2 Domain (Highly Pure)

$895.00

Catalog Number: B2010509 (100 ug)
SARS-CoV-2 Spike S2 Domain is a highly pure recombinant SARS-CoV-2 S2 domain from the origical wild type lineage expressed in insect cells. This product has been used as molecular component of many serological and antigenic assays for SARS-CoV-2. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2010509 Categories: ,

Description

SARS-CoV-2 Spike S2 Domain
Catalog number: B2010509
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 56 kDa
Supplied as: Lyophilized Powder
Applications: molecular component of many serological and antigenic assays for SARS-CoV-2
Storage: -20℃
Keywords: Spike S2, S2 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Walls AC, Park YJ, Tortorici MA, Wall A, McGuire AT, Veesler D. Structure,
Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein. Cell. 2020 Apr
16;181(2):281-292.e6.

2: Xia X. Domains and Functions of Spike Protein in Sars-Cov-2 in the Context of
Vaccine Design. Viruses. 2021 Jan 14;13(1):109.

3: Xia S, Liu M, Wang C, Xu W, Lan Q, Feng S, Qi F, Bao L, Du L, Liu S, Qin C,
Sun F, Shi Z, Zhu Y, Jiang S, Lu L. Inhibition of SARS-CoV-2 (previously
2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor
targeting its spike protein that harbors a high capacity to mediate membrane
fusion. Cell Res. 2020 Apr;30(4):343-355.

4: Daly JL, Simonetti B, Klein K, Chen KE, Williamson MK, Antón-Plágaro C,
Shoemark DK, Simón-Gracia L, Bauer M, Hollandi R, Greber UF, Horvath P, Sessions
RB, Helenius A, Hiscox JA, Teesalu T, Matthews DA, Davidson AD, Collins BM,
Cullen PJ, Yamauchi Y. Neuropilin-1 is a host factor for SARS-CoV-2 infection.
Science. 2020 Nov 13;370(6518):861-865.

5: Buzhdygan TP, DeOre BJ, Baldwin-Leclair A, Bullock TA, McGary HM, Khan JA,
Razmpour R, Hale JF, Galie PA, Potula R, Andrews AM, Ramirez SH. The SARS-CoV-2
spike protein alters barrier function in 2D static and 3D microfluidic in-vitro
models of the human blood-brain barrier. Neurobiol Dis. 2020 Dec;146:105131.

6: Kadam SB, Sukhramani GS, Bishnoi P, Pable AA, Barvkar VT. SARS-CoV-2, the
pandemic coronavirus: Molecular and structural insights. J Basic Microbiol. 2021
Mar;61(3):180-202.

7: Shajahan A, Supekar NT, Gleinich AS, Azadi P. Deducing the N- and
O-glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2.
Glycobiology. 2020 Dec 9;30(12):981-988.

8: Kemp SA, Collier DA, Datir R, Ferreira I, Gayed S, Jahun A, Hosmillo M, Rees-
Spear C, Mlcochova P, Lumb IU, Roberts DJ, Chandra A, Temperton N; CITIID-NIHR
BioResource COVID-19 Collaboration; COVID-19 Genomics UK (COG-UK) Consortium,
Sharrocks K, Blane E, Briggs J, van GM, Smith K, Bradley JR, Smith C, Doffinger
R, Ceron-Gutierrez L, Barcenas-Morales G, Pollock DD, Goldstein RA, Smielewska
A, Skittrall JP, Gouliouris T, Goodfellow IG, Gkrania-Klotsas E, Illingworth C,
McCoy LE, Gupta RK. Neutralising antibodies in Spike mediated SARS-CoV-2
adaptation. medRxiv [Preprint]. 2020 Dec 29:2020.12.05.20241927.

9: Zhou H, Chen X, Hu T, Li J, Song H, Liu Y, Wang P, Liu D, Yang J, Holmes EC,
Hughes AC, Bi Y, Shi W. A Novel Bat Coronavirus Closely Related to SARS-CoV-2
Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein.
Curr Biol. 2020 Jun 8;30(11):2196-2203.e3.
10: Huang Y, Yang C, Xu XF, Xu W, Liu SW. Structural and functional properties
of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19.
Acta Pharmacol Sin. 2020 Sep;41(9):1141-1149.

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