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Prorenin Protein (Human Recombinant)

$895.00

Catalog Number: B2010572 (100 ug)
Prorenin Protein (Human Recombinant) is a highly pure human prorenin expressed in HEK293 cells. This product has been used as molecular tool in the study of the renin-angiotensin system. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2010572 Categories: ,

Description

Prorenin Protein (Human Recombinant)
Catalog number: B2010572
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 44 kDa
Supplied as: Solution
Applications: molecular tool in the study of the renin-angiotensin system
Storage: -20C
Keywords: Pro renin, Angiotensin forming enzyme, Angiotensinogenase, Renin precursor renal
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Burdman I, Burckhardt BB. Prorenin and active renin levels in paediatrics: a
bioanalytical review. Clin Chem Lab Med. 2020 Aug 19;59(2):275-285.

2: Wiegel RE, von Versen-Höynck F, Steegers-Theunissen RPM, Steegers EAP, Danser
AHJ. Prorenin periconceptionally and in pregnancy: Does it have a physiological
role? Mol Cell Endocrinol. 2021 Feb 15;522:111118.

3: Wilkinson-Berka JL, Miller AG, Fletcher EL. Prorenin and the (pro)renin
receptor: do they have a pathogenic role in the retina? Front Biosci (Elite Ed).
2010 Jun 1;2:1054-64.

4: Sun Y, Goes Martini A, Janssen MJ, Garrelds IM, Masereeuw R, Lu X, Danser
AHJ. Megalin: A Novel Endocytic Receptor for Prorenin and Renin. Hypertension.
2020 May;75(5):1242-1250.

5: Burdman I, Burckhardt BB. Human pro_renin determination by hybrid
immunocapture liquid chromatography/mass spectrometry: A mixed-solvent-triggered
digestion utilizing D-optimal design. Rapid Commun Mass Spectrom. 2020 Dec
30;34(24):e8932.

6: Ichihara A, Sakoda M, Mito-Kurauchi A, Itoh H. Activated pro_renin as a
therapeutic target for diabetic nephropathy. Diabetes Res Clin Pract. 2008 Nov
13;82 Suppl 1:S63-6.

7: Jan Danser AH, Batenburg WW, van Esch JH. Prorenin and the (pro)renin
receptor–an update. Nephrol Dial Transplant. 2007 May;22(5):1288-92.

8: Ichihara A, Kaneshiro Y, Suzuki F. Pro_renin receptor blockers: effects on
cardiovascular complications of diabetes and hypertension. Expert Opin Investig
Drugs. 2006 Oct;15(10):1137-9.

9: Nabi AH, Suzuki F. Biochemical properties of renin and prorenin binding to
the (pro)renin receptor. Hypertens Res. 2010 Feb;33(2):91-7.
10: Catanzaro DF. Physiological relevance of renin/prorenin binding and uptake.
Hypertens Res. 2005 Feb;28(2):97-105.

Products Related to Prorenin Protein (Human Recombinant): Proteins

Ordering Information

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4- Order by phone: 1-858-900-3210 (6 am – 8 pm PST).

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