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MUC1 Protein (Human with mFc Tag)

$595.00

Catalog Number: B2010496 (100 ug)
MUC1 Protein (Human with mFc Tag) is a highly pure human recombinant MUC1 protein (expressed in HEK293 cells) fused to the Fc region of mouse IgG. This product has been used as a key molecular component in the study of intracellular signaling as well as the study of protective mucous barriers on epithelial surfaces. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2010496 Categories: ,

Description

MUC1 Protein (Human with mFc Tag)
Catalog number: B2010496
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 41 kDa + Fc tag
Supplied as: Lyophilized Powder
Applications: a molecular component in the study of intracellular signaling as well as the study of protective mucous barriers on epithelial surfaces.
Storage: −20°C
Keywords: MUC-1 Protein, MUC1/ZD Protein, ADMCKD Protein, MUC-1/X Protein, MCD Protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Agrawal B, Gupta N, Konowalchuk JD. MUC1 Mucin: A Putative Regulatory
(Checkpoint) Molecule of T Cells. Front Immunol. 2018 Oct 22;9:2391.

2: Nath S, Mukherjee P. MUC1: a multifaceted oncoprotein with a key role in
cancer progression. Trends Mol Med. 2014 Jun;20(6):332-42.

3: Nabavinia MS, Gholoobi A, Charbgoo F, Nabavinia M, Ramezani M, Abnous K.
Anti-MUC1 aptamer: A potential opportunity for cancer treatment. Med Res Rev.
2017 Nov;37(6):1518-1539.

4: Gao T, Cen Q, Lei H. A review on development of MUC1-based cancer vaccine.
Biomed Pharmacother. 2020 Dec;132:110888.

5: Taylor-Papadimitriou J, Burchell JM, Graham R, Beatson R. Latest developments
in MUC1 immunotherapy. Biochem Soc Trans. 2018 Jun 19;46(3):659-668.

6: Dhar P, McAuley J. The Role of the Cell Surface Mucin MUC1 as a Barrier to
Infection and Regulator of Inflammation. Front Cell Infect Microbiol. 2019 Apr
24;9:117.

7: Kim KC, Lillehoj EP. MUC1 mucin: a peacemaker in the lung. Am J Respir Cell
Mol Biol. 2008 Dec;39(6):644-7.

8: Yousefi M, Dehghani S, Nosrati R, Zare H, Evazalipour M, Mosafer J, Tehrani
BS, Pasdar A, Mokhtarzadeh A, Ramezani M. Aptasensors as a new sensing
technology developed for the detection of MUC1 mucin: A review. Biosens
Bioelectron. 2019 Apr 1;130:1-19.

9: Sirviö E, Mikkonen JJW, Koistinen AP, Miinalainen I, Kullaa AM. Localization
of transmembrane mucin MUC1 on the apical surface of oral mucosal cells.
Ultrastruct Pathol. 2019;43(4-5):184-189.
10: Scholfield DP, Simms MS, Bishop MC. MUC1 mucin in urological malignancy. BJU
Int. 2003 Apr;91(6):560-6.

Products Related to MUC1 Protein (Human with mFc Tag): Proteins

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