Lubricin Antibody, Bovine

Product Description

Lubricin Antibody, Bovine
Catalog number: B2026970
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 0.1 mg/mL
Supplied as: Solution
Storage: −20°C
Keywords: PRG4, Proteoglycan 4, SZP, Superficial zone protein, Articular superficial zone protein, Megakaryocyte stimulating factor, MSF, CACP, HAPO, JCAP, bG174L6.2, FLJ32635, Hemangiopoietin, Lubricin, Q92954

References:
“1. Jay GD, Waller KA. The biology of lubricin: near frictionless joint motion. Matrix Biol. 2014;39:17-24.
2. Swann DA, Silver FH, Slayter HS, Stafford W, Shore E. The molecular structure and lubricating activity of lubricin isolated from bovine and human synovial fluids. Biochem J. 1985;225(1):195-201.
3. Elsaid KA, Jay GD, Warman ML, Rhee DK, Tortorella MD. The role of lubricin in the mechanical behavior of synovial joints. Osteoarthritis Cartilage. 2007;15(5):544-555.
4. Rhee DK, Marcelino J, Baker M, Gong Y, Smits P, Lefebvre V, et al. The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth. J Clin Invest. 2005;115(3):622-631.
5. Waller KA, Zhang LX, Fleming BC, Jay GD. Preventing post-traumatic osteoarthritis: efficacy of a single intra-articular injection of lubricin in a rat model of anterior cruciate ligament transection. Osteoarthritis Cartilage. 2013;21(8):1013-1020.
6. Marcelino J, Carpten JD, Suwairi WM, Gutierrez OM, Schwartz S, Robbins C, et al. CACP syndrome is caused by mutations in PRG4, expression of which is necessary for synovial joint development and maintenance. Nat Genet. 1999;23(3):319-322.
7. Zappone M, Ruths M, Chen GW, Jay GD, Israelachvili JN. Adsorption, lubrication, and wear of lubricin on model surfaces: polymer brush-like behavior of a glycoprotein. Biophys J. 2007;92(11):3829-3839.
8. Flannery CR, Hughes CE, Schumacher BL, Tudor D, Aydelotte MB, Kuettner KE, et al. Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and lubricin. Biochem Biophys Res Commun. 1999;254(3):535-541.
9. Coles JM, Zhang L, Blum JJ, Warman ML, Jay GD, Guilak F, et al. Loss of boundary lubrication of cartilage in mice lacking lubricin. Arthritis Rheum. 2010;62(6):1666-1674.
10. Jay GD, Tantravahi U, Britt DE, Barrach HJ, Cha CJ. Homology of lubricin and superficial zone protein (SZP): evidence for a single gene (PRG4) product. J Orthop Res. 2001;19(4):677-687.”
Lubricin Antibody, Bovine

Products Related to Lubricin Antibody, Bovine can be found at Antibodies