L-Histidinol Dihydrochloride

Product Description

L-Histidinol Dihydrochloride
Catalog number: B2017021
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 g
Molecular Weight or Concentration: 214.10 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: RT
Keywords: L-Histidinol Dihydrochloride
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Ghodge SV, Fedorov AA, Fedorov EV, Hillerich B, Seidel R, Almo SC, Raushel FM. Structural and mechanistic characterization of L-histidinol phosphate phosphatase from the polymerase and histidinol phosphatase family of proteins Biochemistry. 2013 Feb 12;52(6):1101-12.
2: Warrington RC, Cheng I, Fang WD. Effects of L-histidinol on the susceptibility of P815 mastocytoma cells to selected anticancer drugs in vitro and in DBA/2J mice J Natl Cancer Inst. 1987 Jun;78(6):1177-83.
3: Nagai A, Scheidegger A. Purification and characterization of histidinol dehydrogenase from cabbage Arch Biochem Biophys. 1991 Jan;284(1):127-32.
4: Omi R, Goto M, Miyahara I, Manzoku M, Ebihara A, Hirotsu K. Crystal structure of monofunctional histidinol phosphate phosphatase from Thermus thermophilus HB8 Biochemistry. 2007 Nov 6;46(44):12618-27.
5: Warrington RC, Fang WD. Reversal of the multidrug-resistant phenotype of Chinese hamster ovary cells by L-histidinol J Natl Cancer Inst. 1989 May 10;81(10):798-803.
6: Henderson GB, Snell EE. Crystalline L-histidinol phosphate aminotransferase from Salmonella typhimurium. Purification and subunit structure J Biol Chem. 1973 Mar 25;248(6):1906-11.
7: Monti SM, De Simone G, D’Ambrosio K. L-Histidinol Dehydrogenase as a New Target for Old Diseases Curr Top Med Chem. 2016;16(21):2369-78.
8: Warrington RC. L-histidinol in experimental cancer chemotherapy: improving the selectivity and efficacy of anticancer drugs, eliminating metastatic disease and reversing the multidrug-resistant phenotype Biochem Cell Biol. 1992 May;70(5):365-75.
9: Grubmeyer C, Skiadopoulos M, Senior AE. L-histidinol dehydrogenase, a Zn2+-metalloenzyme Arch Biochem Biophys. 1989 Aug 1;272(2):311-7.
10: Kohnoe S, Maehara Y, Takahashi I, Yoshida M, Emi Y, Baba H, Sugimachi K. L-histidinol potentiates hyperthermic cell-killing in-vitro Int J Oncol. 1993 Nov;3(5):835-9.

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