Insulin-like Growth Factor Binding Protein-4 (N-Terminal)


Catalog Number: B2010570 (0.1 mg)
Insulin-like Growth Factor Binding Protein-4 (N-Terminal) is a highly pure N-terminal fragment of insulin-like growth factor binding protein-4 (IGFBP-4). This product has been used as molecular tool in the study of IGFBP family of proteins. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2010570 Category:


insulin-like growth factor binding protein-4 (N-Terminal)
Catalog number: B2010570
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: 15 kDa
Supplied as: Lyophilized
Applications: molecular tool in the study of IGFBP family of proteins
Storage: -20C
Keywords: NT-IGFBP-4
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Austin K, Tsang D, Chalmers JA, Maalouf MF, Brubaker PL. Insulin-like growth
factor-binding protein-4 inhibits epithelial growth and proliferation in the
rodent intestine. Am J Physiol Gastrointest Liver Physiol. 2018 Aug

2: Durai R, Davies M, Yang W, Yang SY, Seifalian A, Goldspink G, Winslet M.
Biology of insulin-like growth factor binding protein-4 and its role in cancer
(review). Int J Oncol. 2006 Jun;28(6):1317-25.

3: Li H, Yu S, Hao F, Sun X, Zhao J, Xu Q, Duan D. Insulin-like growth factor
binding protein 4 inhibits proliferation of bone marrow mesenchymal stem cells
and enhances growth of neurospheres derived from the stem cells. Cell Biochem
Funct. 2018 Aug;36(6):331-341.

4: You Q, Wu Y, Yao N, Shen G, Zhang Y, Xu L, Li G, Ju C. Interaction of AIM
with insulin-like growth factor-binding protein-4. Int J Mol Med. 2015

5: Mohan S, Baylink DJ. Serum insulin-like growth factor binding protein
(IGFBP)-4 and IGFBP-5 levels in aging and age-associated diseases. Endocrine.
1997 Aug;7(1):87-91.

6: Wu T, Xie C, Han J, Ye Y, Singh S, Zhou J, Li Y, Ding H, Li QZ, Zhou X,
Putterman C, Saxena R, Mohan C. Insulin-Like Growth Factor Binding Protein-4 as
a Marker of Chronic Lupus Nephritis. PLoS One. 2016 Mar 28;11(3):e0151491.

7: Sato H, Sakaeda M, Ishii J, Kashiwagi K, Shimoyamada H, Okudela K, Tajiri M,
Ohmori T, Ogura T, Woo T, Masuda M, Hirata K, Kitamura H, Yazawa T. Insulin-like
growth factor binding protein-4 gene silencing in lung adenocarcinomas. Pathol
Int. 2011 Jan;61(1):19-27.

8: Bach LA. Insulin-Like Growth Factor Binding Proteins–an Update. Pediatr
Endocrinol Rev. 2015 Dec;13(2):521-30.

9: Contois LW, Nugent DP, Caron JM, Cretu A, Tweedie E, Akalu A, Liebes L,
Friesel R, Rosen C, Vary C, Brooks PC. Insulin-like growth factor binding
protein-4 differentially inhibits growth factor-induced angiogenesis. J Biol
Chem. 2012 Jan 13;287(3):1779-89.
10: Hjortebjerg R, Lindberg S, Pedersen S, Mogelvang R, Jensen JS, Oxvig C,
Frystyk J, Bjerre M. Insulin-Like Growth Factor Binding Protein 4 Fragments
Provide Incremental Prognostic Information on Cardiovascular Events in Patients
With ST-Segment Elevation Myocardial Infarction. J Am Heart Assoc. 2017 Mar

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