Human ZIPK Protein Active

Description

Human ZIPK Protein Active
Catalog number: B2014148
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 μg
Molecular Weight or Concentration: 64.3 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: ZIPK Protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Barman MK, Chand K, Mitra D. Zipper interacting protein kinase (ZIPK) is a negative regulator of HIV-1 replication that is restricted by viral Nef protein through proteasomal degradation Biochem Biophys Res Commun. 2022 Oct 15;625:122-127.
2: Wu W, Hu H, Ye Z, Leong M, He M, Li Q, Hu R, Zhang S. Zipper-interacting protein kinase interacts with human cell division cycle 14A phosphatase Mol Med Rep. 2015 Apr;11(4):2775-80.
3: Haystead TA. ZIP kinase, a key regulator of myosin protein phosphatase 1 Cell Signal. 2005 Nov;17(11):1313-22.
4: Ihara E, Edwards E, Borman MA, Wilson DP, Walsh MP, MacDonald JA. Inhibition of zipper-interacting protein kinase function in smooth muscle by a myosin light chain kinase pseudosubstrate peptide Am J Physiol Cell Physiol. 2007 May;292(5):C1951-9.
5: Fan H, Ou Q, Su Q, Li G, Deng Z, Huang X, Bi J. ZIPK activates the IL-6/STAT3 signaling pathway and promotes cisplatin resistance in gastric cancer cells FEBS Open Bio. 2021 Sep;11(9):2655-2667.
6: Weitzel DH, Chambers J, Haystead TA. Phosphorylation-dependent control of ZIPK nuclear import is species specific Cell Signal. 2011 Jan;23(1):297-303.
7: Borman MA, MacDonald JA, Haystead TA. Staurosporine inhibition of zipper-interacting protein kinase contractile effects in gastrointestinal smooth muscle Biochem Cell Biol. 2007 Feb;85(1):111-20.
8: Zhang Y, Zhang C, Zhang H, Zeng W, Li S, Chen C, Song X, Sun J, Sun Z, Cui C, Cao X, Zheng L, Wang P, Zhao W, Zhang Z, Xu Y, Zhu M, Chen H. ZIPK mediates endothelial cell contraction through myosin light chain phosphorylation and is required for ischemic-reperfusion injury FASEB J. 2019 Aug;33(8):9062-9074.
9: Zeng W, Sun Z, Ma T, Song X, Li S, Zhang Q, Yuan W, Li J, Liu L, Zhu M, Chen H. Elevated ZIPK is required for TNF–induced cell adhesion molecule expression and leucocyte adhesion in endothelial cells Acta Biochim Biophys Sin (Shanghai). 2021 Apr 15;53(5):567-574.
10: Carr BW, Basepayne TL, Chen L, Jayashankar V, Weiser DC. Characterization of the zebrafish homolog of zipper interacting protein kinase Int J Mol Sci. 2014 Jun 30;15(7):11597-613.

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