Human Troponin C (Recombinant)

Description

Human Troponin C (Recombinant)
Catalog number: B2014193
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: ~18 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Troponin C (Recombinant)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Jeong KY, Kim CR, Un S, Yi MH, Lee IY, Park JW, Hong CS, Yong TS. Allergenicity of recombinant troponin C from Tyrophagus putrescentiae Int Arch Allergy Immunol. 2010;151(3):207-13.
2: Liu S, Zhang MY, Song Q, Ling M, Kadijevic L, Shi Q. Recombinant single chain cardiac troponin I-C polypeptides: superior calibration and control materials for cardiac troponin I immunoassays Clin Lab. 2001;47(1-2):19-27.
3: Li MX, Chandra M, Pearlstone JR, Racher KI, Trigo-Gonzalez G, Borgford T, Kay CM, Smillie LB. Properties of isolated recombinant N and C domains of chicken troponin C Biochemistry. 1994 Feb 1;33(4):917-25.
4: Dohet C, al-Hillawi E, Trayer IP, R_egg JC. Reconstitution of skinned cardiac fibres with human recombinant cardiac troponin-I mutants and troponin-C FEBS Lett. 1995 Dec 18;377(2):131-4.
5: Yan C, Sack JS. X-ray structure of a human cardiac muscle troponin C/troponin I chimera in two crystal forms Acta Crystallogr F Struct Biol Commun. 2022 Jan 1;78(Pt 1):17-24.
6: Wang ZY, Sarkar S, Gergely J, Tao T. Ca2(+)-dependent interactions between the C-helix of troponin-C and troponin-I. Photocross-linking and fluorescence studies using a recombinant troponin-C J Biol Chem. 1990 Mar 25;265(9):4953-7.
7: Finley N, Abbott MB, Abusamhadneh E, Gaponenko V, Dong W, Gasmi-Seabrook G, Howarth JW, Rance M, Solaro RJ, Cheung HC, Rosevear PR. NMR analysis of cardiac troponin C-troponin I complexes: effects of phosphorylation FEBS Lett. 1999 Jun 18;453(1-2):107-12.
8: Galiska A, Hatch V, Craig R, Murphy AM, Van Eyk JE, Wang CL, Lehman W, Foster DB. The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments Circ Res. 2010 Mar 5;106(4):705-11.
9: Gulati J, Babu A, Putkey JA. Down-regulation of fast-twitch skeletal muscle fiber with cardiac troponin-C and recombinant mutants. Structure/function studies with site-directed mutagenesis FEBS Lett. 1989 May 8;248(1-2):5-8.
10: Baxley T, Johnson D, Pinto JR, Chalovich JM. Troponin C Mutations Partially Stabilize the Active State of Regulated Actin and Fully Stabilize the Active State When Paired with 14 TnT Biochemistry. 2017 Jun 13;56(23):2928-2937.

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