Human Sirtuin 1 Protein


Catalog Number: B2011070 (50 ug)
Human Sirtuin 1 Protein is a highly pure recombinant human Sirtuin 1 (amino acids 193- 741 with a GST tag) expressed in E. coli. This product has been used as molecular tool for various chemical, biochemical and immunological applications. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2011070 Categories: ,


Human Sirtuin 1 Protein
Catalog number: B2011070
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 ug
Molecular Weight or Concentration: 87.2 kDa
Supplied as: Solution
Applications: molecular tool for various chemical, biochemical and immunological applications
Storage: -20 °C
Keywords: Sirtuin 1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Chen C, Zhou M, Ge Y, Wang X. SIRT1 and aging related signaling pathways Mech Ageing Dev. 2020 Apr;187:111215.
2: Lee SH, Lee JH, Lee HY, Min KJ. Sirtuin signaling in cellular senescence and aging BMB Rep. 2019 Jan;52(1):24-34.
3: Tang BL. Sirt1 and the Mitochondria Mol Cells. 2016 Feb;39(2):87-95.
4: Alves-Fernandes DK, Jasiulionis MG. The Role of SIRT1 on DNA Damage Response and Epigenetic Alterations in Cancer Int J Mol Sci. 2019 Jun 28;20(13):3153.
5: Ding RB, Bao J, Deng CX. Emerging roles of SIRT1 in fatty liver diseases Int J Biol Sci. 2017 Jul 6;13(7):852-867.
6: Jiao F, Gong Z. The Beneficial Roles of SIRT1 in Neuroinflammation-Related Diseases Oxid Med Cell Longev. 2020 Sep 14;2020:6782872.
7: Kauppinen A, Suuronen T, Ojala J, Kaarniranta K, Salminen A. Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders Cell Signal. 2013 Oct;25(10):1939-48.
8: Mustafa Rizvi SH, Shao D, Tsukahara Y, Pimentel DR, Weisbrod RM, Hamburg NM, McComb ME, Matsui R, Bachschmid MM. Oxidized GAPDH transfers S-glutathionylation to a nuclear protein Sirtuin-1 leading to apoptosis Free Radic Biol Med. 2021 Oct;174:73-83.
9: Devi K, Singh N, Jaggi AS. Dual role of sirtuin 1 in inflammatory bowel disease Immunopharmacol Immunotoxicol. 2020 Oct;42(5):385-391.
10: Engin-Ustun Y, Ozgu-Erdinc AS, Kiyak Caglayan E, Gulerman C, Sarikaya E, Aktulay A, Demirtas C, Erkaya S, Yilmaz N. Sirtuin 1 Levels in Recurrent Implantation Failure Rev Bras Ginecol Obstet. 2017 Oct;39(10):541-544.

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