Human Hepatocyte Growth Factor

Product Description

Human Hepatocyte Growth Factor
Catalog number: B2010336
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Human Hepatocyte Growth Factor expressed in CHO. This protein acts as a cytokine that bonds to the Met tyrosine kinase receptor, and exhibits biological activities.
Storage: -20C
Keywords: rHuHGF; Hepatopoietin-A; SF
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Kitamura K, Nagoshi N, Tsuji O, Matsumoto M, Okano H, Nakamura M. Application
of Hepatocyte Growth Factor for Acute Spinal Cord Injury: The Road from Basic
Studies to Human Treatment. Int J Mol Sci. 2019 Feb 28;20(5):1054.

2: Ido A, Numata M, Kodama M, Tsubouchi H. Mucosal repair and growth factors:
recombinant human hepatocyte growth factor as an innovative therapy for
inflammatory bowel disease. J Gastroenterol. 2005 Oct;40(10):925-31.

3: Wright JW, Church KJ, Harding JW. Hepatocyte Growth Factor and Macrophage-
stimulating Protein “Hinge” Analogs to Treat Pancreatic Cancer. Curr Cancer Drug
Targets. 2019;19(10):782-795.

4: Wang LS, Wang H, Zhang QL, Yang ZJ, Kong FX, Wu CT. Hepatocyte Growth Factor
Gene Therapy for Ischemic Diseases. Hum Gene Ther. 2018 Apr;29(4):413-423.

5: Palestino-Dominguez M, Pelaez-Luna M, Lazzarini-Lechuga R, Rodriguez-Ochoa I,
Souza V, Miranda RU, Perez-Aguilar B, Bucio L, Marquardt JU, Gomez-Quiroz LE,
Gutierrez-Ruiz MC. Recombinant human hepatocyte growth factor provides
protective effects in cerulein-induced acute pancreatitis in mice. J Cell
Physiol. 2018 Dec;233(12):9354-9364.

6: Lin XY, Wang H, Tan Y. [Role of Hepatocyte_Growth Factor in Wound Repair].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2018 Dec 20;40(6):822-826.

7: Mei L, He Y, Wang H, Jin Y, Wang S, Jin C. Human hepatocyte_growth factor
inhibits early neointima formation in rabbit abdominal aortae following
ultrasound-guided balloon injury. Mol Med Rep. 2017 Oct;16(4):5203-5210.

8: Pfander D, Cramer T, Weseloh G, Pullig O, Schuppan D, Bauer M, Swoboda B.
Hepatocyte growth_factor in human osteoarthritic cartilage. Osteoarthritis
Cartilage. 1999 Nov;7(6):548-59.

9: Imamura R, Matsumoto K. Hepatocyte growth factor in physiology and infectious
diseases. Cytokine. 2017 Oct;98:97-106.
10: Gerritsen ME, Tomlinson JE, Zlot C, Ziman M, Hwang S. Using gene expression
profiling to identify the molecular basis of the synergistic actions of
hepatocyte growth factor and vascular endothelial growth factor in human
endothelial cells. Br J Pharmacol. 2003 Oct;140(4):595-610.

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