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Human GRO alpha/CXCL1 (Recombinant)

$495.00

Catalog Number: B2010365 (10 ug)
Human GRO alpha/CXCL1 is a high quality research product used as highly pure Human GRO alpha/CXCL1 expressed in E. coli. This protein acts as a protein with putative roles in inflammation, angiogenesis, tumorigenesis, and wound healing. Custom bulk orders of this product are available upon request.

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SKU: B2010365 Categories: , ,

Description

Human GRO alpha/CXCL1
Catalog number: B2010365
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Human GRO alpha/CXCL1 expressed in E. coli. This protein acts as a protein with putative roles in inflammation, angiogenesis, tumorigenesis, and wound healing.
Storage: -20C
Keywords: HuGRO-α/CXCL1; NAP-3; MGSA; Growth-regulated alpha protein
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Lo HM, Lai TH, Li CH, Wu WB. TNF-α induces CXCL1 chemokine expression and
release in human vascular endothelial cells in vitro via two distinct signaling
pathways. Acta Pharmacol Sin. 2014 Mar;35(3):339-50.

2: Kanda Y, Koike K, Sakamoto Y, Osako Y, Masuhara K, Watanabe K, Tsurufuji S,
Hirota K, Miyake A. GRO-alpha in human serum: differences related to age and
sex. Am J Reprod Immunol. 1997 Jul;38(1):33-8.

3: Filipovic R, Jakovcevski I, Zecevic N. GRO-alpha and CXCR2 in the human fetal
brain and multiple sclerosis lesions. Dev Neurosci. 2003 Mar-Aug;25(2-4):279-90.

4: Losy J, Zaremba J, Skrobański P. CXCL1 (GRO-alpha) chemokine in acute
ischaemic stroke patients. Folia Neuropathol. 2005;43(2):97-102.

5: Yung MM, Tang HW, Cai PC, Leung TH, Ngu SF, Chan KK, Xu D, Yang H, Ngan HY,
Chan DW. GRO-α and IL-8 enhance ovarian cancer metastatic potential via the
CXCR2-mediated TAK1/NFκB signaling cascade. Theranostics. 2018 Feb
2;8(5):1270-1285.

6: Zhou Y, Zhang J, Liu Q, Bell R, Muruve DA, Forsyth P, Arcellana-Panlilio M,
Robbins S, Yong VW. The chemokine GRO-alpha (CXCL1) confers increased
tumorigenicity to glioma cells. Carcinogenesis. 2005 Dec;26(12):2058-68.

7: Fanelli G, Benedetti F, Wang SM, Lee SJ, Jun TY, Masand PS, Patkar AA, Han C,
Serretti A, Pae CU, Fabbri C. Reduced CXCL1/GRO chemokine plasma levels are a
possible biomarker of elderly depression. J Affect Disord. 2019 Apr
15;249:410-417.

8: Lisi S, Sisto M, Lofrumento DD, D’Amore M, De Lucro R, Ribatti D. GRO-α/CXCR2
system and ADAM17 correlated expression in Sjögren’s syndrome. Inflammation.
2013 Jun;36(3):759-66.

9: Geiser T, Dewald B, Ehrengruber MU, Clark-Lewis I, Baggiolini M. The
interleukin-8-related chemotactic cytokines GRO alpha, GRO beta, and GRO gamma
activate human neutrophil and basophil leukocytes. J Biol Chem. 1993 Jul
25;268(21):15419-24.
10: Kuo CH, Lee MS, Kuo HF, Lin YC, Hung CH. Azithromycin suppresses Th1- and
Th2-related chemokines IP-10/MDC in human monocytic cell line. J Microbiol
Immunol Infect. 2019 Dec;52(6):872-879.

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