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Human Fractalkine/CX3CL1 (Recombinant)

$695.00 $495.00

Catalog Number: B2010362 (10 ug)
Human Fractalkine/CX3CL1 is a high quality research product used as highly pure Human Fractalkine/CX3CL1 expressed in E. coli. This protein acts as a protein found associated with inflammatory diseases such as rheumatoid arthritis (RA), rheumatoid vasculitis (RV). Custom bulk orders of this product are available upon request.

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SKU: B2010362 Categories: , ,

Description

Human Fractalkine/CX3CL1
Catalog number: B2010362
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Human Fractalkine/CX3CL1 expressed in E. coli. This protein acts as a protein found associated with inflammatory diseases such as rheumatoid arthritis (RA), rheumatoid vasculitis (RV).
Storage: -20C
Keywords: rHuFractalkine/CX3CL1; Neurotactin; SCYD1; NTT
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Korbecki J, Simińska D, Kojder K, Grochans S, Gutowska I, Chlubek D,
Baranowska-Bosiacka I. Fractalkine/CX3CL1 in Neoplastic Processes. Int J Mol
Sci. 2020 May 25;21(10):3723.

2: Nanki T, Imai T, Kawai S. Fractalkine/CX3CL1 in rheumatoid arthritis. Mod
Rheumatol. 2017 May;27(3):392-397.

3: Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS, Sosman JA,
McDermott DF, Powderly JD, Gettinger SN, Kohrt HE, Horn L, Lawrence DP, Rost S,
Leabman M, Xiao Y, Mokatrin A, Koeppen H, Hegde PS, Mellman I, Chen DS, Hodi FS.
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer
patients. Nature. 2014 Nov 27;515(7528):563-7.

4: Finneran DJ, Nash KR. Neuroinflammation and fractalkine signaling in
Alzheimer’s disease. J Neuroinflammation. 2019 Feb 11;16(1):30.

5: Julia V, Staumont-Salle D, Dombrowicz D. Rôle de la fractalkine/CX3CL1 et de
son récepteur CX3CR1 dans les pathologies allergiques [Role of
fractalkine/CX3CL1 and its receptor CX3CR1 in allergic diseases]. Med Sci
(Paris). 2016 Mar;32(3):260-6. French.

6: Sugaya M, Nakamura K, Mitsui H, Takekoshi T, Saeki H, Tamaki K. Human
keratinocytes express fractalkine/CX3CL1. J Dermatol Sci. 2003 May;31(3):179-87.

7: Hirono K, Imaizumi T, Aizawa T, Watanabe S, Tsugawa K, Shiratori T, Kawaguchi
S, Seya K, Matsumiya T, Ito E, Tanaka H. Endothelial expression of fractalkine
(CX3CL1) is induced by Toll-like receptor 3 signaling in cultured human
glomerular endothelial cells. Mod Rheumatol. 2020 Nov;30(6):1074-1081.

8: Helmke A, Nordlohne J, Balzer MS, Dong L, Rong S, Hiss M, Shushakova N,
Haller H, von Vietinghoff S. CX3CL1-CX3CR1 interaction mediates macrophage-
mesothelial cross talk and promotes peritoneal fibrosis. Kidney Int. 2019
Jun;95(6):1405-1417.

9: Rutti S, Arous C, Schvartz D, Timper K, Sanchez JC, Dermitzakis E, Donath MY,
Halban PA, Bouzakri K. Fractalkine (CX3CL1), a new factor protecting β-cells
against TNFα. Mol Metab. 2014 Aug 11;3(7):731-41.

10: Szukiewicz D, Kochanowski J, Mittal TK, Pyzlak M, Szewczyk G, Cendrowski K.
CX3CL1 (fractalkine) and TNFα production by perfused human placental lobules
under normoxic and hypoxic conditions in vitro: the importance of CX3CR1
signaling. Inflamm Res. 2014 Mar;63(3):179-89.

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