Human Annexin A6 Protein

Product Description

Human Annexin A6 Protein
Catalog number: B2011730
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 0.5 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: ANX 6 protein, ANXA6 protein, ANX A6 protein, Chromobindin 20 protein, Lipocortin VI protein, CBP68 protein, ANX6 protein, AnnexinVI protein, p68 protein, Protein III protein, Annexin A 6, AnnexinA6 protein, Annexin A6, Annexin A-6 protein, CBP 68 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Meier EM, Rein-Fischboeck L, Pohl R, Wanninger J, Hoy AJ, Grewal T, Eisinger K, Krautbauer S, Liebisch G, Weiss TS, Buechler C. Annexin A6 protein is downregulated in human hepatocellular carcinoma Mol Cell Biochem. 2016 Jul;418(1-2):81-90.
2: Smith BN, Topp SD, Fallini C, Shibata H, Chen HJ, Troakes C, King A, Ticozzi N, Kenna KP, Soragia-Gkazi A, Miller JW, Sato A, Dias DM, Jeon M, Vance C, Wong CH, de Majo M, Kattuah W, Mitchell JC, Scotter EL, Parkin NW, Sapp PC, Nolan M, Nestor PJ, Simpson M, Weale M, Lek M, Baas F, Vianney de Jong JM, Ten Asbroek ALMA, Redondo AG, Esteban-Pérez J, Tiloca C, Verde F, Duga S, Leigh N, Pall H, Morrison KE, Al-Chalabi A, Shaw PJ, Kirby J, Turner MR, Talbot K, Hardiman O, Glass JD, De Belleroche J, Maki M, Moss SE, Miller C, Gellera C, Ratti A, Al-Sarraj S, Brown RH Jr, Silani V, Landers JE, Shaw CE. Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis Sci Transl Med. 2017 May 3;9(388):eaad9157.
3: Uchihara T, Miyake K, Yonemura A, Komohara Y, Itoyama R, Koiwa M, Yasuda T, Arima K, Harada K, Eto K, Hayashi H, Iwatsuki M, Iwagami S, Baba Y, Yoshida N, Yashiro M, Masuda M, Ajani JA, Tan P, Baba H, Ishimoto T. Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance Cancer Res. 2020 Aug 15;80(16):3222-3235.
4: Keklikoglou I, Cianciaruso C, Güç E, Squadrito ML, Spring LM, Tazzyman S, Lambein L, Poissonnier A, Ferraro GB, Baer C, Cassará A, Guichard A, Iruela-Arispe ML, Lewis CE, Coussens LM, Bardia A, Jain RK, Pollard JW, De Palma M. Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models Nat Cell Biol. 2019 Feb;21(2):190-202.
5: Grewal T, Hoque M, Conway JRW, Reverter M, Wahba M, Beevi SS, Timpson P, Enrich C, Rentero C. Annexin A6-A multifunctional scaffold in cell motility Cell Adh Migr. 2017 May 4;11(3):288-304.
6: Croissant C, Gounou C, Bouvet F, Tan S, Bouter A. Annexin-A6 in Membrane Repair of Human Skeletal Muscle Cell: A Role in the Cap Subdomain Cells. 2020 Jul 21;9(7):1742.
7: Hoque M, Elmaghrabi YA, Köse M, Beevi SS, Jose J, Meneses-Salas E, Blanco-Muñoz P, Conway JRW, Swarbrick A, Timpson P, Tebar F, Enrich C, Rentero C, Grewal T. Annexin A6 improves anti-migratory and anti-invasive properties of tyrosine kinase inhibitors in EGFR overexpressing human squamous epithelial cells FEBS J. 2020 Jul;287(14):2961-2978.
8: Ma H, Kien F, Manière M, Zhang Y, Lagarde N, Tse KS, Poon LL, Nal B. Human annexin A6 interacts with influenza a virus protein M2 and negatively modulates infection J Virol. 2012 Feb;86(3):1789-801.
9: Enrich C, Rentero C, Grewal T. Annexin A6 in the liver: From the endocytic compartment to cellular physiology Biochim Biophys Acta Mol Cell Res. 2017 Jun;1864(6):933-946.
10: Bandorowicz-Pikuła J, Seliga AK. Annexin A6 as a cholesterol and nucleotide binding protein involved in membrane repair and in controlling membrane transport during endo- and exocytosis Postepy Biochem. 2018 Oct 25;64(3):190-195.

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