Pseudomonas Aeruginosa Elastase

Product Description

Pseudomonas Aeruginosa Elastase
Catalog number: B2026790
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: NA
Supplied as: Powder
Storage: −20°C
Keywords: LasB, Pseudolysin, Neutral metalloproteinase PAE

References:
1. Casilag F, Lorenz A, Krueger J, Klawonn F, Weiss S, Häussler S. The LasB elastase of Pseudomonas aeruginosa acts in concert with alkaline protease AprA to prevent flagellin-mediated immune recognition. Infect Immun. 2016;84(1):162-171.
2. Thayer MM, Flaherty KM, McKay DB. Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution. J Biol Chem. 1991;266(34):2864-2871.
3. Cigana C, Lorè NI, Riva C, De Fino I, Spagnuolo L, Sipione B, et al. Pseudomonas aeruginosa elastase contributes to the establishment of chronic lung colonization and modulates the immune response in a murine model. Front Microbiol. 2021;12:654259.
4. van Dalen CJ, Whitehouse W, Winterbourn CC, Kettle AJ. Pseudomonas aeruginosa elastase down-regulates host inflammatory responses by degrading cytokines and chemokines. Front Immunol. 2021;12:634068.
5. Bever RA, Iglewski BH. Molecular characterization and nucleotide sequence of the Pseudomonas aeruginosa elastase structural gene. J Bacteriol. 1988;170(9):4309-4314.
6. Wretlind B, Pavlovskis OR. Pseudomonas aeruginosa elastase and its role in pseudomonas infections. Rev Infect Dis. 1983;5 Suppl 5:S998-S1004.
7. Peters JE, Park SJ, Darzins A, Freck LC, Saulnier JM, Wallach JM, et al. LasB elastase of Pseudomonas aeruginosa: substrate specificity and a synthetic peptide inhibitor. Mol Microbiol. 1992;6(9):1155-1162.
8. Sawa T, Ohara M, Kurahashi K, Nishio J, Gropper MA, Wiener-Kronish JP. In vitro and in vivo effects of Pseudomonas aeruginosa elastase on lung epithelial cells. Infect Immun. 1998;66(7):3242-3249.
9. Strateva T, Mitov I. Antimicrobial resistance and virulence factors of Pseudomonas aeruginosa: a review. Rev Esp Quimioter. 2011;24(3):119-125.
10. Galdino ACM, Viganor L, de Castro V, Branquinha MH, Santos ALS. Pseudomonas aeruginosa LasB elastase: a major virulence factor and an attractive therapeutic target. Curr Med Chem. 2019;26(19):3371-3388.
PSEUDOMONAS AERUGINOSA ELASTASE

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