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Human ANKRD1 Protein

$795.00

Catalog Number: B2011726 (20 µg)
Human ANKRD1 Protein is a high quality recombinant human ANKRD1 protein His tagged and expressed in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2011726 Categories: ,

Description

Human ANKRD1 Protein
Catalog number: B2011726
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 20 µg
Molecular Weight or Concentration: 38.6 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: ANKRD-1, MCARP protein, ANKRD 1 protein, ANKRD 1, ANKRD1, bA320F15.2 protein, C-193 protein, ANKRD-1 protein, CARP protein, CVARP protein, Ankyrin repeat domain-containing protein 1 protein, ALRP protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Hershberger RE, Jordan E. Dilated Cardiomyopathy Overview 2007 Jul 27 [updated 2022 Apr 7]. In: Adam MP, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews(®) [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2022.
2: Badi I, Cinquetti R, Frascoli M, Parolini C, Chiesa G, Taramelli R, Acquati F. Intracellular ANKRD1 protein levels are regulated by 26S proteasome-mediated degradation FEBS Lett. 2009 Aug 6;583(15):2486-92.
3: Gao J, Collyer J, Wang M, Sun F, Xu F. Genetic Dissection of Hypertrophic Cardiomyopathy with Myocardial RNA-Seq Int J Mol Sci. 2020 Apr 25;21(9):3040.
4: Lei Y, Henderson BR, Emmanuel C, Harnett PR, deFazio A. Inhibition of ANKRD1 sensitizes human ovarian cancer cells to endoplasmic reticulum stress-induced apoptosis Oncogene. 2015 Jan 22;34(4):485-95.
5: Kojic S, Nestorovic A, Rakicevic L, Belgrano A, Stankovic M, Divac A, Faulkner G. A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein Arch Biochem Biophys. 2010 Oct 1;502(1):60-7.
6: Samaras SE, Chen B, Koch SR, Sawyer DB, Lim CC, Davidson JM. 26S proteasome regulation of Ankrd1/CARP in adult rat ventricular myocytes and human microvascular endothelial cells Biochem Biophys Res Commun. 2012 Sep 7;425(4):830-5.
7: Arimura T, Bos JM, Sato A, Kubo T, Okamoto H, Nishi H, Harada H, Koga Y, Moulik M, Doi YL, Towbin JA, Ackerman MJ, Kimura A. Cardiac ankyrin repeat protein gene (ANKRD1) mutations in hypertrophic cardiomyopathy J Am Coll Cardiol. 2009 Jul 21;54(4):334-42.
8: Moulik M, Vatta M, Witt SH, Arola AM, Murphy RT, McKenna WJ, Boriek AM, Oka K, Labeit S, Bowles NE, Arimura T, Kimura A, Towbin JA. ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene J Am Coll Cardiol. 2009 Jul 21;54(4):325-33.
9: Piroddi N, Pesce P, Scellini B, Manzini S, Ganzetti GS, Badi I, Menegollo M, Cora V, Tiso S, Cinquetti R, Monti L, Chiesa G, Bleyl SB, Busnelli M, Dellera F, Bruno D, Caicci F, Grimaldi A, Taramelli R, Manni L, Sacerdoti D, Tesi C, Poggesi C, Ausoni S, Acquati F, Campione M. Myocardial overexpression of ANKRD1 causes sinus venosus defects and progressive diastolic dysfunction Cardiovasc Res. 2020 Jul 1;116(8):1458-1472.
10: Duboscq-Bidot L, Charron P, Ruppert V, Fauchier L, Richter A, Tavazzi L, Arbustini E, Wichter T, Maisch B, Komajda M, Isnard R, Villard E; EUROGENE Heart Failure Network. Mutations in the ANKRD1 gene encoding CARP are responsible for human dilated cardiomyopathy Eur Heart J. 2009 Sep;30(17):2128-36.

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