Human ALDH6A1 Protein

Description

Human ALDH6A1 Protein
Catalog number: B2011579
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 20 µg
Molecular Weight or Concentration: 250 µg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: ALDH6A1 protein, Human ALDH6A1 protein, Recombinant ALDH6A1 protein, Methylmalonate-semialdehyde dehydrogenase acylating mitochondrial isoform 1 protein, MMSADHA protein, MMSDH protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Wang H, Dey KK, Chen PC, Li Y, Niu M, Cho JH, Wang X, Bai B, Jiao Y, Chepyala SR, Haroutunian V, Zhang B, Beach TG, Peng J. Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer’s disease Mol Neurodegener. 2020 Jul 25;15(1):43.
2: Shin H, Cha HJ, Lee MJ, Na K, Park D, Kim CY, Han DH, Kim H, Paik YK. Identification of ALDH6A1 as a Potential Molecular Signature in Hepatocellular Carcinoma via Quantitative Profiling of the Mitochondrial Proteome J Proteome Res. 2020 Apr 3;19(4):1684-1695.
3: Lu J, Chen Z, Zhao H, Dong H, Zhu L, Zhang Y, Wang J, Zhu H, Cui Q, Qi C, Wang S, Chen S, Shao J. ABAT and ALDH6A1, regulated by transcription factor HNF4A, suppress tumorigenic capability in clear cell renal cell carcinoma J Transl Med. 2020 Feb 24;18(1):101.
4: Cho SY, Kang S, Kim DS, Na HJ, Kim YJ, Choi YD, Cho NH. HSP27, ALDH6A1 and Prohibitin Act as a Trio-biomarker to Predict Survival in Late Metastatic Prostate Cancer Anticancer Res. 2018 Nov;38(11):6551-6560.
5: Guo Q, Zhang T, Gong Y, Tao Y, Gao Y, Wang Y, Tian J, Zhang S, Wang H, Rodriguez R, Wang Z. Aldehyde dehydrogenase 6 family member A1 negatively regulates cell growth and to cisplatin sensitivity in bladder cancer Mol Carcinog. 2022 Jul;61(7):690-701.
6: Vasiliou V, Pappa A. Polymorphisms of human aldehyde dehydrogenases. Consequences for drug metabolism and disease Pharmacology. 2000 Sep;61(3):192-8.
7: Bell CC, Santoyo Castelazo A, Yang EL, Maggs JL, Jenkins RE, Tugwood J, O’Neill PM, Naisbitt DJ, Park BK. Oxidative bioactivation of abacavir in subcellular fractions of human antigen presenting cells Chem Res Toxicol. 2013 Jul 15;26(7):1064-72.
8: Timmons JA, Atherton PJ, Larsson O, Sood S, Blokhin IO, Brogan RJ, Volmar CH, Josse AR, Slentz C, Wahlestedt C, Phillips SM, Phillips BE, Gallagher IJ, Kraus WE. A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease Nucleic Acids Res. 2018 Sep 6;46(15):7772-7792.
9: Marcadier JL, Smith AM, Pohl D, Schwartzentruber J, Al-Dirbashi OY; FORGE Canada Consortium, Majewski J, Ferdinandusse S, Wanders RJ, Bulman DE, Boycott KM, Chakraborty P, Geraghty MT. Mutations in ALDH6A1 encoding methylmalonate semialdehyde dehydrogenase are associated with dysmyelination and transient methylmalonic aciduria Orphanet J Rare Dis. 2013 Jul 9;8:98.
10: Zou Y, Lu Q, Yao Q, Dong D, Chen B. Identification of novel prognostic biomarkers in renal cell carcinoma Aging (Albany NY). 2020 Nov 21;12(24):25304-25318.

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