Human ALDH5A1 Protein

Product Description

Human ALDH5A1 Protein
Catalog number: B2011578
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 0.5 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: ALDH5A1 protein (His tag), SSADH protein, ALDH5A1, ALDHA1-5, ALDHA1-5 protein, ALDHA1 5, SSDH protein, mitochondrial, ALDHA1 5 protein, Succinate-semialdehyde dehydrogenase protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Wang X, Zhao Y, Luo J, Xu L, Li X, Jin Y, Li C, Feng M, Wang Y, Chen J, Hou Y, Zhao Q, Zhao J, Ning B, Zheng Y, Yu D. MicroRNA hsa-miR-1301-3p Regulates Human ADH6, ALDH5A1 and ALDH8A1 in the Ethanol-Acetaldehyde-Acetate Metabolic Pathway Mol Pharmacol. 2020 Aug;98(2):120-129.
2: Yu D, Tolleson WH, Knox B, Jin Y, Guo L, Guo Y, Kadlubar SA, Ning B. Modulation of ALDH5A1 and SLC22A7 by microRNA hsa-miR-29a-3p in human liver cells Biochem Pharmacol. 2015 Dec 15;98(4):671-80.
3: Deng XY, Gan XX, Feng JH, Cai WS, Wang XQ, Shen L, Luo HT, Chen Z, Guo M, Cao J, Shen F, Xu B. ALDH5A1 acts as a tumour promoter and has a prognostic impact in papillary thyroid carcinoma Cell Biochem Funct. 2021 Mar;39(2):317-325.
4: Tian X, Han Y, Yu L, Luo B, Hu Z, Li X, Yang Z, Wang X, Huang W, Wang H, Zhang Q, Ma D. Decreased expression of ALDH5A1 predicts prognosis in patients with ovarian cancer Cancer Biol Ther. 2017 Apr 3;18(4):245-251.
5: Brown M, Turgeon C, Rinaldo P, Roullet JB, Gibson KM. Temporal metabolomics in dried bloodspots suggests multipathway disruptions in aldh5a1(-/-) mice, a model of succinic semialdehyde dehydrogenase deficiency Mol Genet Metab. 2019 Dec;128(4):397-408.
6: Martin K, McConnell A, Elsea SH. Assessing Prevalence and Carrier Frequency of Succinic Semialdehyde Dehydrogenase Deficiency J Child Neurol. 2021 Nov;36(13-14):1218-1222.
7: Asai M, Wada Y. [4-Hydroxybutyric aciduria] Ryoikibetsu Shokogun Shirizu. 1998;(18 Pt 1):250-1.
8: Torrens M, Fonseca F. Role of ALDH5A1 in methadone treatment Pharmacogenomics. 2014 Apr;15(5):573-6.
9: Liu N, Kong XD, Kan QC, Shi HR, Wu QH, Zhuo ZH, Bai QL, Jiang M. Mutation analysis and prenatal diagnosis in a Chinese family with succinic semialdehyde dehydrogenase and a systematic review of the literature of reported ALDH5A1 mutations J Perinat Med. 2016 May 1;44(4):441-51.
10: DiBacco ML, Pop A, Salomons GS, Hanson E, Roullet JB, Gibson KM, Pearl PL. Novel ALDH5A1 variants and genotype: Phenotype correlation in SSADH deficiency Neurology. 2020 Nov 10;95(19):e2675-e2682.

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