Human AICDA Protein (Highly Pure)

Product Description

Human AICDA Protein (Highly Pure)
Catalog number: B2011548
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 500 µg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20℃
Keywords: AICDA protein (His tag), Purified recombinant Human AICDA protein (His tag), AID protein, ARP2 protein, HIGM2 protein, CDA2 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Di Noia JM, Neuberger MS. Molecular mechanisms of antibody somatic hypermutation Annu Rev Biochem. 2007;76:1-22.
2: Methot SP, Di Noia JM. Molecular Mechanisms of Somatic Hypermutation and Class Switch Recombination Adv Immunol. 2017;133:37-87.
3: Jourdan M, Caraux A, De Vos J, Fiol G, Larroque M, Cognot C, Bret C, Duperray C, Hose D, Klein B. An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization Blood. 2009 Dec 10;114(25):5173-81.
4: Petersen-Mahrt S. DNA deamination in immunity Immunol Rev. 2005 Feb;203:80-97.
5: Teng G, Papavasiliou FN. Immunoglobulin somatic hypermutation Annu Rev Genet. 2007;41:107-20.
6: Häsler J, Rada C, Neuberger MS. The cytoplasmic AID complex Semin Immunol. 2012 Aug;24(4):273-80.
7: Gajula KS. Designing an Elusive C•G→G•C CRISPR Base Editor Trends Biochem Sci. 2019 Feb;44(2):91-94.
8: Feng Y, Seija N, Di Noia JM, Martin A. AID in Antibody Diversification: There and Back Again Trends Immunol. 2020 Jul;41(7):586-600.
9: Lee-Theilen M, Chaudhuri J. Walking the AID tightrope Nat Immunol. 2010 Feb;11(2):107-9.
10: Maul RW, Gearhart PJ. AID and somatic hypermutation Adv Immunol. 2010;105:159-91.

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