Human 5-Lipoxygenase protein

Product Description

Human 5-Lipoxygenase protein
Catalog number: B2011032
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 500 U
Molecular Weight or Concentration: 78 kDa
Supplied as: Solution
Applications: molecular tool for various chemical, biochemical and immunological applications
Storage: -20°C
Keywords: 5-Lipoxygenase Antigen, 5 Lipoxygenase Recombinant Protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Sun QY, Zhou HH, Mao XY. Emerging Roles of 5-Lipoxygenase Phosphorylation in Inflammation and Cell Death Oxid Med Cell Longev. 2019 Nov 29;2019:2749173.
2: Ochs MJ, Suess B, Steinhilber D. 5-lipoxygenase mRNA and protein isoforms Basic Clin Pharmacol Toxicol. 2014 Jan;114(1):78-82.
3: Häfner AK, Gerstmeier J, Hörnig M, George S, Ball AK, Schröder M, Garscha U, Werz O, Steinhilber D. Characterization of the interaction of human 5-lipoxygenase with its activating protein FLAP Biochim Biophys Acta. 2015 Nov;1851(11):1465-72.
4: Häfner AK, Beilstein K, Graab P, Ball AK, Saul MJ, Hofmann B, Steinhilber D. Identification and Characterization of a New Protein Isoform of Human 5-Lipoxygenase PLoS One. 2016 Nov 17;11(11):e0166591.
5: Merchant N, Bhaskar LVKS, Momin S, Sujatha P, Reddy ABM, Nagaraju GP. 5-Lipoxygenase: Its involvement in gastrointestinal malignancies Crit Rev Oncol Hematol. 2018 Jul;127:50-55.
6: Uebbing S, Kreiß M, Scholl F, Häfner AK, Sürün D, Garscha U, Werz O, Basavarajappa D, Samuelsson B, Rådmark O, Suess B, Steinhilber D. Modulation of microRNA processing by 5-lipoxygenase FASEB J. 2021 Feb;35(2):e21193.
7: Dufrusine B, Di Francesco A, Oddi S, Scipioni L, Angelucci CB, D’Addario C, Serafini M, Häfner AK, Steinhilber D, Maccarrone M, Dainese E. Iron-Dependent Trafficking of 5-Lipoxygenase and Impact on Human Macrophage Activation Front Immunol. 2019 Jun 28;10:1347.
8: Rådmark O. Arachidonate 5-lipoxygenase Prostaglandins Other Lipid Mediat. 2002 Aug;68-69:211-34.
9: Ford-Hutchinson AW, Gresser M, Young RN. 5-Lipoxygenase Annu Rev Biochem. 1994;63:383-417.
10: Lin H, Weng J, Mei H, Zhuang M, Xiao X, Du F, Lin L, Wu J, Chen Z, Huang Y, Chen F, Wang X. 5-Lipoxygenase promotes epithelial-mesenchymal transition through the ERK signaling pathway in gastric cancer J Gastroenterol Hepatol. 2021 Feb;36(2):455-466.

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